Evidence map›Paper›PMID 40904263›Full record

ArticleChemistryOpen2025

Multidirectional in silico and in vitro Research for the Pharmaceutical Potential of Fibigia Clypeata (L.) Medik: Phytochemical, Antimicrobial, and Antimyeloma Properties.

Tuba Unver, Ugur Uzuner, Dilara Akcora-Yildiz, Ismet Gurhan, Caglar Arkan, Zeynep Ozdemir

Abstract read
In one paragraph

Article in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tuba UnverDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Inonu University, 44280, Malatya, Turkiye.ORCID 0000-0002-8655-2716
Ugur UzunerDepartment of Molecular Biology and Genetics, Faculty of Science, Karadeniz Technical University, 61080, Trabzon, Turkiye.ORCID 0000-0002-5308-3730
Dilara Akcora-YildizDepartment of Biology, Faculty of Science & Art, Mehmet Akif Ersoy University, 15200, Burdur, Turkiye.ORCID 0000-0003-2586-4385
Ismet GurhanDepartment of Pharmaceutical Botany, Faculty of Pharmacy, Inonu University, 44280, Malatya, Turkiye.ORCID 0000-0001-7017-2447
Caglar ArkanDepartment of Biology, Faculty of Science & Art, Mehmet Akif Ersoy University, 15200, Burdur, Turkiye.ORCID 0009-0005-5367-0248
Zeynep OzdemirDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280, Malatya, Turkiye.ORCID 0000-0003-4559-2305

Funding

Scientific and Technological Research Council of Turkiye (TUBITAK)
6 · The paper itself

Abstract

Fibigia clypeata (L.) Medik, a member of the Brassicaceae, has been the subject of limited research on its pharmaceutical and medicinal properties. This study aims to evaluate the phytochemical, antimicrobial, and antimyeloma properties of F. clypeata extracts and detail these results in silico analyses. The minimum inhibitory concentration (MIC) of F. clypeata extracts was determined using dilution methods, and antimyeloma activity was determined using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide) assay. The findings were evaluated by in silico analyses and correlated with the results of liquid chromatography-high-resolution mass spectrometry. The inhibitory effect of the water extract (MIC is 15 mg mL

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntineoplastic Agents, PhytogenicBrassicaceaePhytochemicalsPlant ExtractsCandidaCell Line, TumorComputer SimulationHumansMicrobial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic Agents, PhytogenicPhytochemicalsPlant Extractsantimicrobial activityantimyeloma activityFibigia clypeatamolecular dockingnatural pharmaceuticals

Identifiers

PMID40904263
PMCPMC12680575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.