Evidence map›Paper›PMID 40904037›Full record

ArticleMedical physics2025

Effect of immobilization mask and beam energy on dose coverage to small joints in treating osteoarthritis with low-dose radiation therapy.

George X Ding, Kenneth L Homann, Eric T Shinohara

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

George X DingDepartment of Radiation Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Kenneth L HomannDepartment of Radiation Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Eric T ShinoharaDepartment of Radiation Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOsteoarthritis (OA) is the most common form of arthritis, affecting over 32 million Americans. Low dose radiation therapy (LDRT) is being used to treat OA, including small joints. Treatment energies recommended include both orthovoltage and 6 MV photons. This study evaluates treatment plan accuracy of small joints using a commercial treatment planning system (TPS) when 6 MV is used. The effect of bolus and immobilization mask on target dose coverage and the use of 2.5 MV beams are also studied.

methodsMonte Carlo calculated dose distributions were used to evaluate the dose calculation accuracy of small joints by the Varian Eclipse system (AAA V.16) for one patient. The CT based dose calculations with- and without an Aquaplast immobilization mask using 6 MV and 2.5 MV beams were compared. The target dose coverages were analyzed using a dose volume histogram (DVH). The effect of the Aquaplast mask on target dose coverage was evaluated. The doses calculated by Monte Carlo (MC) were regarded as the Gold Standard.

resultsThe dose calculated by the Eclipse system significantly underestimated D

conclusionEclipse calculations are less accurate, and underestimate D

Indexed as

ImmobilizationJointsMasksOsteoarthritisRadiation DosageHumansMonte Carlo MethodRadiotherapy DosageRadiotherapy Planning, Computer-Assisteddose accuracy for small jointsimmobilization masklow dose for osteoarthritisMonte Carlo

Identifiers

PMID40904037
PMCPMC12409234

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.