Evidence map›Paper›PMID 40903953›Full record

ArticleNeural regeneration research2026

Interaction of artificial intelligence, mental disorders, and diverse data modalities: Potential treatment management based on the "method-disease-data" axis.

Xu Tian, Ning Wang, Jin Yan, Yiming Chen, Ke Ma

Abstract read
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xu TianGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Ning WangShandong Co-Innovation Center of Classic TCM formula, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Jin YanDepartment of Rehabilitation Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yiming ChenDepartment of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.
Ke MaShandong Co-Innovation Center of Classic TCM formula, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.ORCID 0000-0003-4942-9281

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although many previous studies have highlighted the advances in prediction models, instruments for pathological and histological diagnosis and treatment, as well as individualized treatment modalities in mental disorders, these previous syntheses usually study the research outcomes separately and ignore the holistic integration of research regarding artificial intelligence technological approaches, data sets used and applications in mental health research. We used the BioBERT pretrained language model to systematically extract relevant information and develop an extensive knowledge graph that includes 3158 entities connected with 3248 different relationships. Our knowledge graph delineates essential artificial intelligence technological frameworks and explicitly maps out the relationships linking artificial intelligence methods, mental disorders, and diverse data modalities. The synthesis, centered on the analytical axis of "method-disease-data," highlights key research areas where artificial intelligence and neuropsychiatry meet. Specifically, it focuses on key applications in early detection, improved accuracy of diagnosis, and individualized therapeutic interventions. In addition, we summarized the applications derived from basic research findings that extend to ongoing clinical trials, revealing the path toward future clinical application in psychiatric work. Importantly, the research paid special attention to the application of artificial intelligence in identifying key brain regions and neural circuits, providing important clues for elucidating the neural mechanisms of mental disorders and developing targeted interventions. Although artificial intelligence presents great opportunities, there are also significant challenges, including imbalanced data sets, ethical issues, and clinical concerns about trustworthiness and transparency. Strategies to address these challenges are proposed, and a perspective on emerging methods enabled by artificial intelligence is provided, which are expected to greatly change the management and treatment of the future.

Indexed as

artificial intelligenceclinical decision supportclinical trialcomputational psychiatryearly diagnosisknowledge discoverypersonalized medicineprecision psychiatrypsychiatric disorderstreatment prediction

Identifiers

PMID40903953
PMCPMC13557679

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.