Evidence map›Paper›PMID 40903902›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2025

Isolated oral CD30

Evandro Bezerra, Ludmila Lupu, Marcos de Lima, Lena Pfaller, Alison Neal, Nelly R Hajizadeh, Qiuhong Zhao, Martin Beibel, Catherine Chung, Myriam Lemmens and 18 more

Abstract readCase Reports
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Evandro BezerraOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Ludmila LupuNovartis Pharma AG, 4056 Basel, Switzerland.
Marcos de LimaOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Lena PfallerNovartis Biomedical Research, 4056 Basel, Switzerland.
Alison NealOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Nelly R HajizadehNovartis Biomedical Research, 4056 Basel, Switzerland.
Qiuhong ZhaoOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Martin BeibelNovartis Biomedical Research, 4056 Basel, Switzerland.
Catherine ChungOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Myriam LemmensNovartis Biomedical Research, Cambridge, MA 02139, USA.
Austin SimOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Mevion OertliNovartis Biomedical Research, 4056 Basel, Switzerland.
Timothy VoorheesOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Rebecca BohnertNovartis Biomedical Research, 4056 Basel, Switzerland.
Nathan DenlingerOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Yoann GilbartNovartis Biomedical Research, 4056 Basel, Switzerland.
Lara BontadelliNovartis Biomedical Research, 4056 Basel, Switzerland.
Laura MonovichOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Jennifer WillertNovartis Pharmaceuticals Corporation, East Hanover, NJ 07936-1080, USA.
Daniel StoverOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Jingbo GaoNovartis Pharmaceuticals Corporation, East Hanover, NJ 07936-1080, USA.
Li LiNovartis Pharmaceuticals Corporation, East Hanover, NJ 07936-1080, USA.
Stefan ReinkerNovartis Biomedical Research, 4056 Basel, Switzerland.
Ulrike NaumannNovartis Biomedical Research, 4056 Basel, Switzerland.
Hans D MenssenNovartis Pharma AG, 4056 Basel, Switzerland.
Daniel JonesOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.
Silvana LibertiniNovartis Biomedical Research, 4056 Basel, Switzerland. Electronic address: silvana.libertini@novartis.com.
Jonathan E BrammerOhio State University James Comprehensive Cancer Center, Columbus, OH 43210, USA.

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

A chimeric antigen receptor (CAR)

Indexed as

Immunotherapy, AdoptiveKi-1 AntigenLymphoma, T-CellReceptors, Chimeric AntigenCD4-Positive T-LymphocytesHumansRemission InductionTreatment OutcomeKi-1 AntigenReceptors, Chimeric Antigencancer-associated genesCAR-T therapyhematologyinsertional mutagenesisintegration site analysislentiviral vectorsT cell lymphoma

Identifiers

PMID40903902
PMCPMC12703168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.