Evidence map›Paper›PMID 40903825›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2025

Perimenopausal symptoms in women with and without ADHD: A population-based cohort study.

Unnur Jakobsdóttir Smári, Unnur Anna Valdimarsdottir, Dora Wynchank, Maxime de Jong, Thor Aspelund, Arna Hauksdottir, Edda Bjork Thordardottir, Gunnar Tomasson, Johanna Jakobsdottir, Donghao Lu and 4 more

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Unnur Jakobsdóttir SmáriCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0009-0001-7151-9622
Unnur Anna ValdimarsdottirCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0001-5382-946X
Dora WynchankPsyQ, Expertise Centre Adult ADHD, The Hague, The Netherlands.ORCID 0000-0003-1098-0180
Maxime de JongPsyQ, Expertise Centre Adult ADHD, The Hague, The Netherlands.ORCID 0000-0003-1168-3559
Thor AspelundCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-7998-5433
Arna HauksdottirCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-4253-1059
Edda Bjork ThordardottirCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0003-3775-9611
Gunnar TomassonCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-1797-7091
Johanna JakobsdottirCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-8019-9683
Donghao LuUnit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-4186-8661
Alicia NevrianaUnit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-3434-2757
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-6851-3297
Sandra KooijPsyQ, Expertise Centre Adult ADHD, The Hague, The Netherlands.ORCID 0000-0002-8644-6323
Helga ZoegaCentre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0003-0761-9028

Funding

Nordforsk 164218Rannís 2511190-051
6 · The paper itself

Abstract

backgroundKnowledge of the impact of perimenopause on women with attention-deficit/hyperactivity disorder (ADHD) is lacking. We compared levels of perimenopausal symptoms and prevalence of severe perimenopausal symptoms among women with and without ADHD across age groups.

methodsIn this cohort study, we used data from the population-based Stress-and-Gene-Analysis cohort study. ADHD diagnosis was self-reported at baseline and 5-year follow-up. At follow-up, we assessed ADHD symptoms using the Adult ADHD Self-Report Scale, perimenopausal symptoms (psychological, somatic, and urogenital) using Menopause Rating Scale (MRS), and general physical symptoms using Patient Health Questionnaire. We described mean scores and mean difference on MRS among women with and without ADHD with linear regression models and contrasted the prevalence of severe perimenopausal symptoms among women with and without ADHD, calculating prevalence ratios (PRs) with 95% confidence intervals (CIs) using modified Poisson regression models.

resultsWomen with ADHD (

conclusionWomen with ADHD have higher prevalence of severe perimenopausal symptoms. These symptoms present at an earlier age than among women without ADHD, indicating an earlier onset age of perimenopause in ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityPerimenopauseAdultCohort StudiesComorbidityFemaleHumansMiddle AgedPrevalenceADHDattention-deficit/hyperactivity disordercomorbiditiesperimenopausal symptomswomen

Identifiers

PMID40903825
PMCPMC12538516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.