Evidence map›Paper›PMID 40903796›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Mechanisms and Pathophysiological Significance of Insulin Resistance in Offspring With Intrauterine Growth Restriction Mediated by Hepatic GR/miR-1224 Programming.

Yongguo Dai, Xiaoling Guo, Pengxia Yu, Dingmei Zhang, Hao Kou, Hui Wang

Erratum issuedAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yongguo DaiDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.ORCID https://orcid.org/0000-0002-9023-5211
Xiaoling GuoDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Pengxia YuDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Dingmei ZhangDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Hao KouDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
Hui WangDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.ORCID https://orcid.org/0000-0001-5300-8661

Funding

Hubei Provincial Natural Science Foundation of China 2024AFB742National Key Research and Development Program of China 2020YFA0803900National Natural Science Foundation of China 82030111National Natural Science Foundation of China 82414020National Natural Science Foundation of China U23A20407
6 · The paper itself

Abstract

Insulin resistance (IR) has fetal origin and gender preference. Here we traced glucose-insulin phenotypical changes of intrauterine growth restriction (IUGR) female offspring at different ages and explore the mechanism. The IUGR model was established by prenatal caffeine exposure (PCE): dams were orally administered caffeine [(30, 120 mg(kg.d)

Indexed as

Fetal Growth RetardationInsulin ResistanceLiverMicroRNAsPrenatal Exposure Delayed EffectsReceptors, GlucocorticoidAnimalsCaffeineDisease Models, AnimalFemaleMalePregnancyRatsSignal TransductionCaffeineMicroRNAsReceptors, Glucocorticoidadvanced glycation end productsglucocorticoidsinsulin resistancemiR‐1224prenatal caffeine exposure

Identifiers

PMID40903796
PMCPMC12667461

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.