Evidence map›Paper›PMID 40903752›Full record

ArticleReproductive health2025

Vitamin D insufficiency in pregnant women from Lebanon: prevalence and key predictors.

Sara Ajjour, Marlene Chakhtoura, Anwar Nassar, Mariam Assaad, Maya Rahme, Cyrus Cooper, Nicholas Harvey, Nawal Tfaily, Taghried Diab, Rihab Al-Tayeh and 1 more

Abstract read
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Article in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sara AjjourCalcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Marlene ChakhtouraCalcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Anwar NassarDepartment of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Mariam AssaadCalcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Maya RahmeCalcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Cyrus CooperMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Nicholas HarveyMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Nawal TfailyDepartment of Obstetrics and Gynecology, Bahman Hospital, Beirut, Lebanon.
Taghried DiabDepartment of Obstetrics and Gynecology, Bahman Hospital, Beirut, Lebanon.
Rihab Al-TayehDepartment of Obstetrics and Gynecology, Bahman Hospital, Beirut, Lebanon.
Ghada El-Hajj FuleihanCalcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. gf01@aub.edu.lb.

Funding

Genetic and Metabolic Determinants of 25(OH)D levels at Baseline and One Year: Findings from a Dose Ranging Vitamin D trialD43TW009118 · FIC · AMERICAN UNIVERSITY OF BEIRUT · PI FULEIHAN, GHADA ELHAJJ · 2012 to 2024
$2.5M
EMRO/WHO under the EMRPPH grant scheme EMIER1409518FIC NIH HHS D43 TW009118In part by NIH D43TW009118
6 · The paper itself

Abstract

backgroundSuboptimal 25-hydroxyvitamin D (25OHD) during pregnancy can have adverse maternal and neonatal outcomes.

aimThis study aimed to estimate the prevalence of vitamin D deficiency in pregnant females in Lebanon and to identify its risk factors.

methodsThis is a cross-sectional study involving pregnant females identified during their first-early second trimester visit to obstetricians in two centers in Beirut. We collected blood samples, anthropometric measurements and lifestyle data. We measured maternal serum 25OHD and used the data to explore possible determinants of deficiency.

resultsWe tested 25OHD levels of 548 females; 270 from American University of Beirut Medical Center and 278 from Bahman hospital. Mean age was 29 ± 5 years and 41.5% were nulliparous. Mean serum 25OHD was 15.4ng/ml and 72.3% had levels < 20 ng/ml. Levels were significantly lower at Bahman hospital, 12.9ng/ml versus 18.1ng/ml at American University of Beirut Medical Center, p-value 0.001. The risk of having 25OHD < 20ng/ml was significantly higher in females from Bahman hospital, those who were veiled, those who smoked and had higher pre-pregnancy body mass index, with a trend for significance for early pregnancy body mass index. This risk decreased for older females, those with higher education, employed females, and those screened during summer/fall. Multivariable logistic regression showed that veiling and younger age were significant risk factors for 25OHD < 20 ng/ml.

conclusionVitamin D deficiency is prevalent in pregnant females from two centers in Beirut. Our findings emphasize the importance of proper screening and supplementation of vitamin D to ensure adequacy throughout pregnancy.

Indexed as

Pregnancy ComplicationsVitamin DVitamin D DeficiencyAdultCross-Sectional StudiesFemaleHumansLebanonPregnancyPrevalenceRisk FactorsYoung Adult25-hydroxyvitamin DVitamin DLebanonMiddle EastPredictorsPregnancyPrevalenceVitamin D

Identifiers

PMID40903752
PMCPMC12406351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.