ReviewEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025
Infectious sacroiliitis: insights from long-term follow-up and the diagnostic contribution of computed tomography and magnetic resonance imaging.
Review in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Shifting risk profiles in the systemic-to-focal transition of brucellosis: a multicenter analysis of spondyloarthritis development.BMC infectious diseases · 2026Article
- Fabrication and Antimycobacterial Evaluation of Molybdenum Disulfide-Coated Titanium Alloy Scaffolds.ACS omega · 2026Article
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Authors and funding
8 authors.
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Abstract
purposeInfectious sacroiliitis (ISI) is a rare condition with non-specific symptoms, often leading to delayed diagnosis We aim to describe the clinical, microbiological, and radiological characteristics of infectious sacroiliitis (ISI), and to highlight the diagnostic and follow-up value of imaging modalities. MATERIALS AND
methodsWe conducted a retrospective review of 35 ISI cases diagnosed over 27 years. Clinical, microbiological, and imaging data were collected. CT and MRI findings were compared, and follow-up imaging was analyzed when available.
resultsThe mean age was 40.9 years, with a female predominance (60%). Pyogenic organisms were identified in 45.7% of cases, Mycobacterium tuberculosis in 34.3%, and Brucella spp. in 20%. The average diagnostic delay was 102 days. The most frequent symptoms were fever (80%) and buttock pain (77.1%), and inflammatory markers were elevated in approximately 90% of cases. Blood cultures were positive in 6.4%, while biopsy and abscess aspiration confirmed the etiological diagnosis in 28.6% and 14.3%, respectively. Imaging played a central role: CT revealed bony erosions (84.6%) and periarticular involvement (69.2%), while MRI, performed in 13 cases, showed signal abnormalities (85.7%), contrast enhancement (91.7%), and detected soft tissue abscesses (30.8%) and extension to adjacent bone or soft tissues (38.5%). Among the 10 patients who underwent both CT and MRI, MRI detected joint space widening more frequently than CT (70% vs. 50%, p = 0.038) and revealed periarticular infiltration in all cases compared to 60% on CT (p = 0.045). Conversely, CT identified bone sequestra in 50% of patients, whereas none were visualized on MRI (p = 0.041). Radiological follow-up showed improvement in 83.3% of cases, although residual lesions persisted.
conclusionISI is difficult to diagnose due to its non-specific presentation. Imaging is essential for early diagnosis, guiding treatment, and monitoring response.
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Registered trials
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