Evidence map›Paper›PMID 40903661›Full record

ArticleActa neurologica Belgica2025

A study of the responsiveness of the Six-Spot Step Test in people with multiple sclerosis.

Esben Køhler, Jacob Callsen, John Kodal Brincks

Abstract read
In one paragraph

Article in Acta neurologica Belgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Esben KøhlerResearch Centre for Care and Rehabilitation, Research Program for Balance and Falls, VIA University College, Hedeager 2, 8200, Aarhus N, Denmark.
Jacob CallsenResearch Centre for Care and Rehabilitation, Research Program for Balance and Falls, VIA University College, Hedeager 2, 8200, Aarhus N, Denmark.
John Kodal BrincksResearch Centre for Care and Rehabilitation, Research Program for Balance and Falls, VIA University College, Hedeager 2, 8200, Aarhus N, Denmark. jobr@via.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to evaluate the responsiveness of the Six-Spot Step Test (SSST) in people with multiple sclerosis to assess its capability as a measure for detecting changes in gait and balance capacity following a 10-week training intervention.

methodsThe SSST, Timed 25-Foot Walk, and mini-BESTest were administered to 71 individuals with MS, ranging from mild to severe disability, before and after a 10-week program of progressive resistance and balance training. However, 16 patients were lost to follow-up. This study adhered to the COSMIN framework for reporting and evaluating the psychometric properties of health-related outcome measures.

resultsSpearman's analyses revealed a moderate negative correlation between changes in the SSST and the mini-BESTest (r

conclusionThe SSST serves as a sensitive measure for changes in gait and balance capacity. Furthermore, the consistently large effect sizes observed across all three gait and balance assessments following the exercise intervention suggest that these measures reflect a shared underlying construct-functional mobility-which is essential for independent community living.

Indexed as

Exercise TestMultiple SclerosisPostural BalanceAdultDisability EvaluationFemaleGaitHumansMaleMiddle AgedWalkingFunctional mobilityMultiple sclerosisResponsivenessThe Six-Spot Step Test

Identifiers

PMID40903661
PMCPMC12644186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.