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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Patient-reported outcomes and their associated factors at 1- and 2-year follow-up after lumbar spine surgery: a surgery registry study.

Ling Jie Cheng, Nick Bansback, Gabriel Ka Po Liu, Wenru Wang, Vivien Xi Wu, Nan Luo, Hwee Weng Dennis Hey

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Preoperative health-related quality of life across four degenerative lumbar conditions in a multi-ethnic Southeast Asian surgical cohort: a cross-sectional SF-36 analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Factors associated with preoperative health-related quality of life in patients undergoing lumbar spine surgery: a multi-ethnic Asian cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ling Jie ChengNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID http://orcid.org/0000-0002-5338-578X
Nick BansbackSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Singapore, 117549, Singapore.ORCID http://orcid.org/0000-0002-1510-3462
Gabriel Ka Po LiuUniversity Spine Centre, Department of Orthopaedic Surgery, National University Hospital, 1E Kent Ridge Road, NUHS Tower Block Level 11, Singapore, 119228, Singapore.
Wenru WangAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-0265-8215
Vivien Xi WuAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-9264-3630
Nan LuoSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, Singapore, 117549, Singapore. ephln@nus.edu.sg.ORCID http://orcid.org/0000-0001-7980-6979
Hwee Weng Dennis HeyUniversity Spine Centre, Department of Orthopaedic Surgery, National University Hospital, 1E Kent Ridge Road, NUHS Tower Block Level 11, Singapore, 119228, Singapore. doshhwd@nus.edu.sg.ORCID http://orcid.org/0000-0002-2012-9835

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDegenerative lumbar conditions are a leading cause of disability worldwide, often requiring surgery when conservative treatments fail. Data on surgical outcomes from patients' perspectives and influencing factors remain limited. This study aimed to assess 1-year and 2-year Patient-Reported Outcomes (PROs) following lumbar spine surgery and identify factors associated with these outcomes.

methodsThis surgery registry study included 1,195 adult patients who underwent lumbar spine surgery between 2017 and 2022 at a tertiary hospital in Singapore. Patients completed the EQ-5D-3L and Oswestry Disability Index before surgery, as well as one year (n = 741) and two years (n = 440) after surgery. Multivariable logistic regression identified factors influencing PRO improvements at the dimension level.

resultsThe mean age of the patients was 58.1 years (SD 16.1). From baseline to 1-year, patients experienced the largest improvements in pain/discomfort (δ = 0.55-0.56) and social functioning (δ = 0.48-0.53), while improvements in activities of daily living and functional tasks were smaller, with negligible change in lifting (δ = 0.04); these effects largely persisted at the 2-year follow-up. Patients with poorer baseline PROs consistently improved across all PROs at the 1-year follow-up. Higher education and conditions affecting only the L4/5 spinal level were associated with better outcomes in activities of daily living, pain/discomfort, and social functioning. Higher education and a prolapsed disc diagnosis were associated with functional task improvements. At year two, poorer baseline PROs remained influential, while the absence of comorbidities emerged as a significant factor.

conclusionsSubstantial improvements in pain/discomfort and social functioning domains occurred within the first year and persisted into year two, while physically demanding tasks such as lifting remained difficult to restore. Patients with poorer baseline PROs and higher education derived the greatest benefit, emphasising tailored pre-operative interventions to optimise outcomes.

Indexed as

Lumbar VertebraePatient Reported Outcome MeasuresActivities of Daily LivingAdultAgedDisability EvaluationFemaleFollow-Up StudiesHumansMaleMiddle AgedQuality of LifeRegistriesSingaporeTreatment OutcomeDegenerative lumbar conditionsLumbar surgeryPatient-centred carePatient-reported outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.