ArticleEuropean radiology2026
Biodegradable stents for biliary strictures after pediatric liver transplantation: a multicenter retrospective study.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Intervention in the Native and Transplant Liver in Children: An Update.Cardiovascular and interventional radiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesBiodegradable biliary stents are used to treat benign biliary strictures in adults. However, there is limited data regarding their use in pediatric patients. This study aims to assess the efficacy and safety of biodegradable biliary stents following pediatric liver transplantation (pLT). MATERIALS AND
methodsConsecutive pLT patients with benign biliary strictures were retrospectively evaluated in five tertiary centers between October 2014 and May 2024. All patients underwent percutaneous bilioplasty followed by the placement of self-expanding polydioxanone-based stents. Stricture features and treatment timing were assessed, as well as freedom from stricture recurrence and complications.
resultsA total of 102 patients (52 males, 50 females; median age at treatment = 5 years, interquartile range (IQR) = 2-11 years) were included. At baseline, 58/102 (57%) had a stricture length ≥ 10 mm, and 53/102 (52%) had intrahepatic duct involvement. Stenting was performed a median of 55 days (IQR = 15-128 days) following biliary drainage. Technically successful stent placement was achieved in 101/102 (99%) cases, and low-grade complications occurred in 19/102 (19%). During a median follow-up of 793 days (IQR = 341-1529 days), 24/102 (24%) patients had stricture recurrence with an estimated median time to recurrence of 2915 days. Eight patients were lost to follow-up before recurrence. Logistic regression did not identify any factors that were independent predictors of stricture recurrence, while Cox regression showed that recoil/residual stenosis was independently associated with earlier recurrence (p = 0.005; HR = 5.334; 95% CI = 1.674-17).
conclusionBiodegradable stents appear safe and effective for treating biliary strictures after pLT. Certain factors may contribute to failure and should inform patient selection and the optimal timing for stenting. KEY POINTS: Question The management of biliary strictures after pediatric liver transplantation (pLT) poses several challenges due to the frailty of the population and refractoriness of the condition. Findings In this multicenter study self-expanding biodegradable biliary stents made of polydioxanone proved to be safe and effective for the treatment of biliary strictures after pLT. Clinical relevance Biodegradable biliary stents may improve the management of biliary strictures after pLT with a positive impact on outcomes and less invasiveness; some factors may help to predict the outcome and define the best timing for stenting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.