Evidence map›Paper›PMID 40903573›Full record

ArticleNature2025

Commensal yeast promotes Salmonella Typhimurium virulence.

Kanchan Jaswal, Olivia A Todd, Roberto C Flores Audelo, William Santus, Saikat Paul, Ciera M Duffy, Edward T Eshoo, Manmeet Singh, Jian Miao, David M Underhill and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Frontiers in cellular and infection microbiology · 2026
    Article
  12. A regulator of amino acid catabolism controlsbioRxiv : the preprint server for biology · 2025
    Article
  13. Infection and immunity · 2025
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kanchan JaswalDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.ORCID 0000-0002-0681-3956
Olivia A ToddDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
Roberto C Flores AudeloDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
William SantusDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
Saikat PaulDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA.
Ciera M DuffyDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
Edward T EshooDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA.
Manmeet SinghDepartment of Pathology, University of Illinois Chicago, Chicago, IL, USA.
Jian MiaoPharmaceutical Sciences Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN, USA.
David M UnderhillDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-2989-658X
Brian M PetersDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0002-0445-2077
Judith BehnsenDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, USA. jbehnsen@uic.edu.ORCID 0000-0003-0109-1090

Funding

Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GARY D. WU · 1997 to 2026
$32.5M
TRAINING PROGRAM IN LUNG BIOLOGY AND PATHOBIOLOGYT32HL007829 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOLLY MEHTA · 1995 to 2026
$15.6M
Exploring the role, regulation, and antimicrobial function of Paneth cell peptides PYY and NPY in maintaining gut microbial commensalism and innate immune defenseR01DK113788 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Joseph F PIERRE · 2017 to 2026
$4.6M
Role of microbial-modulated bile acid receptor signaling in breast cancerR01CA253329 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Katherine Loree Cook, Liza Makowski-Hayes · 2020 to 2026
$3.0M
Candidalysin: a key mediator of Candida vaginitis immunopathologyR01AI134796 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Brian M Peters · 2018 to 2026
$2.9M
Fungal-bacterial dynamics driving dysregulated host responses and lethal synergismR01AI177615 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JAMES E CASSAT, PAUL L FIDEL · 2024 to 2026
$2.4M
Probing short and long term consequences of Small and Large Bowel Microbiota Transplants on Host Physiology: Implications for the development of future live biotherapeuticsR01DK138072 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG, Kristina Brooke Martinez-Guryn · 2024 to 2026
$2.1M
Probing the role of commensal intestinal fungi during Salmonella pathogenesisR01AI143641 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEHNSEN, JUDITH · 2019 to 2023
$2.0M
Inter-kingdom interactions of Salmonella Typhimurium and Candida albicans in the gutR01AI175223 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Judith Behnsen · 2024 to 2026
$1.6M
NCATS NIH HHS UL1 TR002003NCI NIH HHS R01 CA253329NHLBI NIH HHS T32 HL007829NIAID NIH HHS R01 AI134796NIAID NIH HHS R01 AI143641NIAID NIH HHS R01 AI175223NIAID NIH HHS R01 AI177615NIDDK NIH HHS P30 DK050306NIDDK NIH HHS R01 DK113788NIDDK NIH HHS R01 DK138072
6 · The paper itself

Abstract

Enteric pathogens engage in complex interactions with the host and the resident microbiota to establish gut colonization

Indexed as

Candida albicansSalmonella InfectionsSalmonella typhimuriumSymbiosisAnimalsArginineBacterial ProteinsCecumFemaleFimbriae, BacterialHumansMaleMiceMice, Inbred C57BLType III Secretion SystemsVirulenceArginineBacterial ProteinsType III Secretion Systems

Identifiers

PMID40903573
PMCPMC12460169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.