Evidence map›Paper›PMID 40903568›Full record

ArticleNature2025

A circuit that integrates drive state and social contact to gate mating.

Lindsey D Salay, Doris Y Tsao, David J Anderson

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Neural circuits for mammalian parental behaviour.Nature reviews. Neuroscience · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lindsey D SalayDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Doris Y TsaoHoward Hughes Medical Institute, Chevy Chase, MD, USA.ORCID 0000-0003-1083-1919
David J AndersonDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. wuwei@caltech.edu.ORCID 0000-0001-6175-3872

Funding

Region-Specific, Inducible Axonal Tract-Tracing in the BrainR01MH070053 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI David J Anderson · 2004 to 2026
$9.7M
Circuit basis of social behavior decision-making in a subcortical networkR01NS123916 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSON, DAVID J · 2021 to 2025
$2.9M
Multimodal, integrated analysis of neural activity and naturalistic social behavior in freely moving miceR01MH123612 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANDERSON, DAVID J, PERONA, PIETRO · 2020 to 2024
$2.1M
NIMH NIH HHS R01 MH070053NIMH NIH HHS R01 MH123612NINDS NIH HHS R01 NS123916
6 · The paper itself

Abstract

Internal motive states, such as sexual arousal, drive behaviour in response to social cues. However, little is known about how internal states and external cues are integrated to release appropriate behaviours at the correct moment during a social interaction, such as the transition from the appetitive to the consummatory phases of mating

Indexed as

Sexual Behavior, AnimalSocial InteractionAnimalsCuesFemaleHypothalamusMaleMiceMice, Inbred C57BLNeural PathwaysNeuronsPreoptic AreaThalamic Nuclei

Identifiers

PMID40903568
PMCPMC12507686

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.