ArticleNature cardiovascular research2025
p22
Abstract read
In one paragraph
Article in Nature cardiovascular research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- The functional role of the circular RNA circCDR1as targeting SERCA2a in the progression of pathological cardiac hypertrophy and heart failure.Journal of translational medicine · 2026Article
- Reduced Myocardial Serine Synthesis Impairs Functional, Metabolic, and Redox Adaptations to Cardiac Stress.bioRxiv : the preprint server for biology · 2026Article
- 4E-BP inhibition ameliorates heart failure through translational upregulation of SERCA2a and modulation of mitochondrial redox signaling in cardiomyocytes.Redox biology · 2026Article
- New Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging.Pharmaceutical research · 2026Review
- Review
- Inhibition of PAI-1 shifts cardiomyocyte fate from senescence toward apoptosis and mitigates doxorubicin-induced cardiotoxicity.Geromedicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Yasuki Nakada *Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID http://orcid.org/0000-0003-0510-6923
Allen Sam Titus *Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID http://orcid.org/0000-0001-8149-3895
Wataru MizushimaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Yanfei YangDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Peiyong ZhaiDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Yimin TianDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Shinichi OkaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Toshihide KashiharaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Nadezhda FefelovaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.ORCID http://orcid.org/0000-0002-1895-2443
Sri Harika PamarthiDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Tong LiuCenter for Advanced Proteomics Research, Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School and Cancer Institute of New Jersey, Newark, NJ, USA.
Hong LiCenter for Advanced Proteomics Research, Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School and Cancer Institute of New Jersey, Newark, NJ, USA.ORCID http://orcid.org/0000-0001-5731-5335
Lai-Hua XieDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Koichiro TakayamaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Soichiro IkedaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Masato MatsushitaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA.
Chun Yang HuangDivision of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Chiao-Po HsuDivision of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Kenji OnoueDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Yoshihiko SaitoDepartment of Cardiovascular Medicine, Nara Medical University, Kashihara, Japan.
Junichi SadoshimaDepartment of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, NJ, USA. sadoshju@njms.rutgers.edu.ORCID http://orcid.org/0000-0003-3724-4132
Funding
Cysteine oxidation in the heartR01HL091469 · NHLBI · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI Junichi Sadoshima · 2008 to 2026
$9.4MThe Role of Serine Signaling in Compensatory Cardiac HypertrophyR01HL112330 · NHLBI · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI Junichi Sadoshima · 2012 to 2026
$7.5MRemoval of damaged mitochondria by alternative autophagyR01HL138720 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SADOSHIMA, JUNICHI · 2017 to 2024
$4.7MGSK-3beta inhibits lipotoxicityR01HL144626 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Junichi Sadoshima · 2019 to 2026
$3.0MPPARα induces IL-6 to trigger diabetic cardiomyopathyR01HL150881 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SADOSHIMA, JUNICHI · 2020 to 2023
$2.2MAmerican Heart Association (American Heart Association, Inc.) 35120374Fondation Leducq 15CVD04NHLBI NIH HHS R01 HL091469NHLBI NIH HHS R01 HL112330NHLBI NIH HHS R01 HL138720NHLBI NIH HHS R01 HL144626NHLBI NIH HHS R01 HL150881U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 112330U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 138720U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 144626U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 150881U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) 91469
Abstract
Sarcoplasmic/endoplasmic reticulum (SR/ER) Ca
Indexed as
Cytochrome b GroupHeart FailureMyocytes, CardiacNADPH OxidasesSarcoplasmic Reticulum Calcium-Transporting ATPasesAnimalsDisease Models, AnimalHumansMaleMiceMice, Inbred C57BLMice, KnockoutOxidation-ReductionOxidative StressProteolysisSarcoplasmic ReticulumAtp2a2 protein, mouseCyba protein, mouseCytochrome b GroupNADPH OxidasesSarcoplasmic Reticulum Calcium-Transporting ATPasesUbiquitin-Protein Ligases
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.