ReviewNature reviews. Endocrinology2026
Unravelling the rise in thyroid cancer incidence and addressing overdiagnosis.
Review in Nature reviews. Endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- The incidence and perinatal outcomes of pregnancy-associated thyroid cancer: an Australian population-based study.Journal of the Endocrine Society · 2026Article
- Heme oxygenase-1 in thyroid cancer: a context-dependent regulator.Journal of endocrinological investigation · 2026Review
- Case report and literature review of synchronous follicular and papillary thyroid carcinoma with metastasis to femur.Discover oncology · 2026Article
- Thyroid cancer risk in people living with HIV: a systematic review and meta-analysis of global population-based registry studies.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Review
- Fear of cancer recurrence in papillary thyroid cancer: a comparison across ATA risk groups and influencing factors.Endocrine · 2026Article
- Article
- Review
- The Thyroid Under Pressure: Heavy Metals, Endocrine Disruptors and Translational Insights into Carcinogenesis and Thyroid Dysfunctions.International journal of molecular sciences · 2026Review
- Active surveillance for low-risk papillary thyroid carcinoma: Integrating guidelines, emerging evidence, and directions.iScience · 2026Review
- Surgical Management and Outcomes in Advanced Thyroid Cancer: Insights from a Single-Institution Experience.Journal of clinical medicine · 2026Article
- CD8+ T cells in Hashimoto's thyroiditis-associated papillary thyroid carcinoma.European thyroid journal · 2026Article
- Review
- Ethnic Background as a Determinant of Thyroid Cancer Risk: A Decade-Long National Cohort Study Reveals Divergent Epidemics in Saudi Arabia.Saudi medical journal · 2026Article
- The Brazilian Transition in Differentiated Thyroid Carcinoma Management: A 25-Year Nationwide Analysis of Declining High-Activity Radioiodine Use (2000-2024).Archives of endocrinology and metabolism · 2026Article
- Article
- Postoperative serum oxidative stress measures in women with papillary thyroid cancer.Frontiers in endocrinology · 2026Article
- Research on the role and mechanisms of Cystatin 6 in disease pathosis and development.Frontiers in molecular biosciences · 2026Review
- Pre-diagnostic vitamin D deficiency and subsequent thyroid cancer risk: a propensity-matched cohort study.Frontiers in nutrition · 2026Article
- FAM19A5 is an independent prognostic biomarker in thyroid cancer.American journal of translational research · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The global incidence of thyroid cancer has risen sharply since the 1980s, whereas thyroid cancer mortality rates have remained relatively stable. Much of the increase in incidence can be attributed to overdiagnosis of small and indolent papillary thyroid cancers, which has largely been driven by widespread (and sometimes inappropriate) use of imaging studies, especially thyroid and neck ultrasonography. To a lesser extent, increases in the incidence rate of advanced-stage thyroid cancer over the past four decades have also contributed to the observed trends. This Review describes changes in the incidence of thyroid cancer over the past 40 years, outlines well-known and potential risk factors, including obesity and environmental exposures, and explores strategies to address the public-health issues of overdiagnosis and the consequent overtreatment of thyroid cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.