Evidence map›Paper›PMID 40903441›Full record

ArticleThoracic cancer2025

C-Arm Cone Beam CT-Guided Preoperative Microcoil Pulmonary Ground Glass Nodule Localization: Diagnostic and Surgical Advantage.

Carlo Altomare, Rebecca Casati, Giuseppina Pacella, Laura Olivieri, Angelo Tirabasso, Annamaria Altomare, Luca Frasca, Filippo Longo, Pierfilippo Crucitti, Eliodoro Faiella and 2 more

Abstract read
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carlo AltomareUnit of Diagnostic Imaging and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.ORCID https://orcid.org/0009-0002-0919-1504
Rebecca CasatiUnit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Giuseppina PacellaUnit of Diagnostic Imaging and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Laura OlivieriUnit of Diagnostic Imaging and Interventional Radiology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Angelo TirabassoDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, National Institute for Insurance Against Accidents at Work, Rome, Italy.
Annamaria AltomareUnit of Gastroenterology, Università Campus Bio-Medico di Roma, Rome, Italy.
Luca FrascaUnit of Thoracic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Filippo LongoUnit of Thoracic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Pierfilippo CrucittiUnit of Thoracic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Eliodoro FaiellaUnit of Diagnostic Imaging and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Bruno Beomonte ZobelUnit of Diagnostic Imaging and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Rosario Francesco GrassoUnit of Diagnostic Imaging and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the effectiveness and safety of C-arm cone beam CT (CBCT)-guided microcoil localization combined with uniportal video-assisted thoracoscopic surgery (VATS) for the management of small, difficult-to-localize ground-glass opacities (GGOs) and sub-solid nodules in the lungs.

methodsWe retrospectively analyzed data from 13 patients with single, small, peripheral, non-subpleural GGOs or SSN. All patients underwent successful microcoil localization using CB-CT guidance followed by uniportal VATS resection. A microcoil was positioned partly in the lung parenchyma and partly in the extra-pleural space to assist in intraoperative localization. We evaluated the rate of correct microcoil placement and the technical success of the resection.

resultsMicrocoil placement was successfully performed in all patients, with an average procedure time of 28.8 ± 10.8 min. The mean nodule size was 9.9 ± 5.4 mm, and 76.9% of the nodules were classified as ground-glass opacities. No intraparenchymal bleeding was observed, and four patients (30.8%) experienced pneumothorax, all of which were self-limited and required no intervention or coil repositioning. The uniVATS resection success rate was 100%.

conclusionCBCT-guided microcoil localization, with partial placement of the coil in the extra-pleural space, proved to be a highly effective technique for the localization and resection of small pulmonary nodules. The procedure demonstrated high accuracy, minimal complications, reduction of procedural time, and short hospital stays. Intraoperative fluoroscopy was never necessary, with a high reduction in radiation exposure for the patient and the operator. Further studies with larger populations and longer follow-ups are needed to validate these findings.

Indexed as

Cone-Beam Computed TomographyLung NeoplasmsSolitary Pulmonary NoduleThoracic Surgery, Video-AssistedAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studiescone beam CTimage‐guided surgerymicrocoil localizationminimally invasive surgerypreoperative localizationpulmonary nodulethoracic surgeryuniportal VATS

Identifiers

PMID40903441
PMCPMC12408194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.