Evidence map›Paper›PMID 40903395›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles.

Ting Xu, Chunhong Zhu, Xinqi Zhou, Zhiyi Chen, Xianyang Gan, Xiaobing Cui, Feng Zhou, Ran Zhang, Weihua Zhao, Xiaodong Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ting XuFaculty of Psychology, Southwest University, Chongqing 400715, China tingxu.uestc@outlook.com fengty0@swu.edu.cn.ORCID 0000-0003-1590-9025
Chunhong ZhuFaculty of Psychology, Southwest University, Chongqing 400715, China.
Xinqi ZhouInstitute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu 610066, China.ORCID 0000-0002-5032-9141
Zhiyi ChenFaculty of Psychology, Southwest University, Chongqing 400715, China.
Xianyang GanCenter for Information in Medicine, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Xiaobing CuiKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.
Feng ZhouFaculty of Psychology, Southwest University, Chongqing 400715, China.
Ran ZhangFaculty of Psychology, Southwest University, Chongqing 400715, China.
Weihua ZhaoCenter for Information in Medicine, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Xiaodong ZhangCenter for Information in Medicine, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China.
Hong ChenFaculty of Psychology, Southwest University, Chongqing 400715, China.
Qinghua HeFaculty of Psychology, Southwest University, Chongqing 400715, China.
Xu LeiFaculty of Psychology, Southwest University, Chongqing 400715, China.
Jiang QiuFaculty of Psychology, Southwest University, Chongqing 400715, China.ORCID 0000-0003-0269-5910
Tingyong FengFaculty of Psychology, Southwest University, Chongqing 400715, China tingxu.uestc@outlook.com fengty0@swu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the hyper- and hypo-reward or punishment sensitivities (RS, PS) have received considerable attention as prominent transdiagnostic features of psychopathology, the lack of an overarching neurobiological characterization currently limits their early identification and neuromodulation. Here we combined microarray data from the Allen Human Brain Atlas with a multimodal fMRI approach to uncover the neurobiological signatures of RS and PS in a discovery-replication design (

Indexed as

BrainConnectomeGenetic VariationNeurotransmitter AgentsPunishmentRewardAdolescentAdultFemaleHumansMagnetic Resonance ImagingMaleNerve NetYoung AdultNeurotransmitter AgentsfMRIfunctional connectomegene expressionneurosciencepunishment sensitivityreward sensitivity

Identifiers

PMID40903395
PMCPMC12509494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.