Evidence map›Paper›PMID 40903393›Full record

ArticleJournal of natural products2025

Mitrephorines A-E and Other Cytotoxic Aporphinoids from the Bark of

Watchara Sangsopha, Paratchata Batsomboon, Chatphorn Theppitak, Surasak Prachya, Dhanushka Darshana, Chulabhorn Mahidol, Somsak Ruchirawat

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Watchara SangsophaLaboratory of Natural Products, Chulabhorn Research Institute, Bangkok 10210, Thailand.ORCID 0000-0003-0491-5761
Paratchata BatsomboonLaboratory of Medicinal Chemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.ORCID 0000-0001-6470-9084
Chatphorn TheppitakLaboratory of Medicinal Chemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Surasak PrachyaLaboratory of Natural Products, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Dhanushka DarshanaDepartment of Pharmacy, Faculty of Allied Health Sciences, University of Ruhuna, Galle 80000, Sri Lanka.
Chulabhorn MahidolLaboratory of Natural Products, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Somsak RuchirawatLaboratory of Medicinal Chemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Six previously undescribed alkaloids, including three dimeric aporphine alkaloids, mitrephorines A-C (

Indexed as

AlkaloidsAntineoplastic Agents, PhytogenicAporphinesPlant BarkCell Line, TumorCrystallography, X-RayDiterpenesDrug Screening Assays, AntitumorHeLa CellsHep G2 CellsHumansMolecular StructureAlkaloidsAntineoplastic Agents, PhytogenicAporphinesDiterpenes

Identifiers

PMID40903393
PMCPMC12481564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.