Evidence map›Paper›PMID 40901954›Full record

ArticleScience advances2025

The discovery of a

Beth Nicholson, José F Santé, Elizabeth H Chaney, Justin C Deme, Shayna R Deecker, Kristina Sztanko, Alan R Davidson, Susan M Lea, Alexander W Ensminger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pathogens (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beth NicholsonDepartment of Biochemistry, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0009-0009-6586-5121
José F SantéDepartment of Biochemistry, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0009-0008-0983-0816
Elizabeth H ChaneyDepartment of Molecular Genetics, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0009-0008-2031-0942
Justin C DemeCenter for Structural Biology, Center for Cancer Research, National Cancer Institute, Boyles Street, Frederick, MD 21702, USA.ORCID 0000-0001-8811-9871
Shayna R DeeckerDepartment of Biochemistry, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0000-0002-1234-1123
Kristina SztankoDepartment of Molecular Genetics, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0009-0006-4356-1942
Alan R DavidsonDepartment of Biochemistry, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0000-0002-0744-9199
Susan M LeaCenter for Structural Biology, Center for Cancer Research, National Cancer Institute, Boyles Street, Frederick, MD 21702, USA.ORCID 0000-0001-9287-8053
Alexander W EnsmingerDepartment of Biochemistry, University of Toronto, 661 University Ave., Toronto, Ontario M5G 1M1, Canada.ORCID 0000-0003-0824-3704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host cells provide intracellular bacteria with protection from harsh environmental conditions and immune responses, but for many intracellular pathogens, this protection does not appear to be absolute as once thought. Bacteriophages that can kill bacteria inside host cells have been identified for pathogens including

Indexed as

BacteriophagesLegionellaLegionella pneumophilaLegionnaires' DiseaseCryoelectron MicroscopyHost SpecificityHumansVirulence

Identifiers

PMID40901954
PMCPMC12407071

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.