Evidence map›Paper›PMID 40901874›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria.

Alfonso Mendaña, María Santos-Merino, Raquel Gutiérrez-Lanza, Marina Domínguez-Quintero, Juan Manuel Medina-Méndez, Ana González-Guerra, Víctor Campa, Miguel Baez, Magaly Ducos-Galand, Rocío López-Igual and 6 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Suppressor analysis inFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alfonso Mendaña *Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0009-0002-0872-4882
María Santos-Merino *Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0000-0002-9624-2914
Raquel Gutiérrez-LanzaInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0000-0003-0290-7020
Marina Domínguez-QuinteroInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.
Juan Manuel Medina-MéndezInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0000-0002-3548-7491
Ana González-GuerraInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.
Víctor CampaInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.
Miguel BaezInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.
Magaly Ducos-GalandInstitut Pasteur, Université Paris Cité, CNRS UMR3525, Unité Plasticité du Génome Bactérien, Paris 75015, France.
Rocío López-IgualInstitut Pasteur, Université Paris Cité, CNRS UMR3525, Unité Plasticité du Génome Bactérien, Paris 75015, France.
Daniel C VolkeThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens, Lyngby 2800, Denmark.ORCID 0000-0003-0244-2534
Muriel GuggerInstitut Pasteur, Université Paris Cité, Collection of Cyanobacteria, Paris 75015, France.ORCID 0000-0001-6728-1976
Pablo I NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens, Lyngby 2800, Denmark.ORCID 0000-0002-9313-7481
Didier MazelInstitut Pasteur, Université Paris Cité, CNRS UMR3525, Unité Plasticité du Génome Bactérien, Paris 75015, France.ORCID 0000-0001-6482-6002
Fernando de la CruzInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0000-0003-4758-6857
Raúl Fernández-LópezInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-Consejo Superior de Investigaciones Científicas, Santander, Cantabria 39011, Spain.ORCID 0000-0002-9624-9059

Funding

Ministerio de Ciencia, Innovación y Universidades (MCIU) PID2019-110216 GB-I00Ministerio de Ciencia, Innovación y Universidades (MCIU) TED2021-130689B-C31
6 · The paper itself

Abstract

Circadian clocks allow organisms to anticipate daily fluctuations in light and temperature, but how this anticipatory role promotes adaptation to different environments remains poorly understood. Here, we subjected the cyanobacterium

Indexed as

Adaptation, PhysiologicalCircadian ClocksCircadian RhythmMutationSynechococcusBacterial ProteinsCarbon DioxideGene Expression Regulation, BacterialLightBacterial ProteinsCarbon Dioxidecircadian rhythmCyanobacteriaexperimental evolution

Identifiers

PMID40901874
PMCPMC12435244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.