Observational studyBlood transfusion = Trasfusione del sangue
Efficiency in packed red blood management for brain tumor resection: multicenter prospective cohort study (TScoreBTR).
Observational study in Blood transfusion = Trasfusione del sangue. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05832450 (Validation of a Predictive Model to Calculate the Risk of Red Blood Cells Concentrates Transfusion in Patients Undergoing Elective Brain Tumours Resections), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Validation of a Predictive Model to Calculate the Risk of Red Blood Cells Concentrates Transfusion in Patients Undergoing Elective Brain Tumours Resections
Who cites it
1 citing paper in PubMed.
- Appropriate preoperative transfusion requests: an unsolved issue.Blood transfusion = Trasfusione del sangueArticle
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are no optimized patient blood management (PBM) protocols for brain tumor resection (BTR). The aim of this study was to compare the prevalence of packed red cells (PRCs) units reserved with the prevalence of transfusion during BTR and analyse preoperative anemia. MATERIALS AND
methodsProspective observational multicentre study for adult patients who underwent elective BTR. Fourteen tertiary-level hospitals participated from March 2021 to February 2024. The primary outcomes were the prevalence of PRCs reserved and transfused, and the efficiency metrics: crossmatch to transfusion ratio (C/T ratio), transfusion probability (TP), and transfusion index (TI). The secondary outcome was the prevalence of preoperative anemia. CLINICALTRIALS: gov (NCT05832450).
resultsWe analysed data from 1,384 patients. A percentage of 83.3% of them had PRCs units reserved, with a median (range) of 2 (1 to 8) units per patient. The prevalence of intraoperative transfusion was 6.6% (95% CI: 5.4 to 8.0%). There were a significantly inefficient processes with a high C/T ratio (14.85), low TP (7.9%), and low TI (0.14). The percentage of women requiring at least one PRCs transfusion was more than double that of men (9.3 vs 3.7%, p<0.001). The prevalence of preoperative anemia was 25.4% with a statistically significant difference in anemia seen between women and men (36.6 vs 13.6%, p<0.001). When adjusting for preoperative hemoglobin and presumptive diagnosis, the difference between women and men was not significant (OR 1.58 [95% CI: 0.94 to 2.63], p=0.083). DISCUSSION: Systematic PRCs unit reservation remains a common practice despite the low prevalence of transfusions for BTR in Spain. A high prevalence of preoperative anemia was found, particularly among women. We need objective criteria for PBM to allow optimal crossmatching and PRCs reservation for BTR and to subsequently reduce inefficiencies in perioperative PRCs management.
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