Trial reportThe American journal of sports medicine2025
Medial Meniscal Extrusion Increased on 6-Month Magnetic Resonance Imaging, Despite Successful Posterior Root Repair With or Without a Centralization Suture: A Randomized Controlled Clinical Trial.
Trial report in The American journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05088525 (Meniscal Root Tears), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Meniscal Root Tears: Evaluating Meniscal Extrusion After Root Repair with and Without Transtibial Peripheral Stabilization Sutures Using Ultrahigh Magnetic Fields: a Randomized Controlled Trial
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Postoperative rehabilitation after transtibial pullout repair of medial meniscus posterior root tears: A systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Pooled it
- Combined Arthroscopic Medial Meniscal Root Repair and Centralization Using All-Suture Anchors Without a Posteromedial Portal.Arthroscopy techniques · 2026Article
- Arthroscopic Repair of Meniscal Medial Root Tears: The Necessity of Concomitant Realignment Osteotomy.Journal of orthopaedic case reports · 2026Review
- The post-arthroscopic knee: fundamental imaging concepts and emerging techniques.Skeletal radiology · 2026Review
- Radiologic and Clinical Analysis of Posterior Medial Meniscal Root Tears: A Comparative Study of All-Suture Anchor and Transtibial Pullout Techniques.Orthopaedic journal of sports medicine · 2026Article
- Delayed Surgical Treatment of Pediatric and Adolescent Medial Meniscus Posterior Root Tears Is Associated With Increased Odds of Medial Tibiofemoral Compartment Cartilage Injury: A Multicenter Study.The American journal of sports medicine · 2026Article
- Alignment-dependent changes in tibiofemoral contact mechanics after selective medial soft tissue release during medial meniscus posterior root repair: an exploratory human cadaveric study.International orthopaedics · 2026Article
- Larger preoperative medial meniscus extrusion is associated with insufficient pain relief following pullout repair for medial meniscus posterior root tears.Journal of experimental orthopaedics · 2026Article
- Subcortical Bone Cysts at the Medial Meniscus Posterior Root Are Associated with Longer Symptom Duration but Not with Healing Status or Meniscal Extrusion After Root Repair.Medicina (Kaunas, Lithuania) · 2026Article
- There Is No Clinical and Radiological Difference between Suspensory and Cortical Button Fixation at the Treatment of Medial Meniscus Posterior Root Tear.Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026Article
- Meniscal Extrusion: A Key Modifiable Driver of Meniscal and Cartilage Degeneration.Current reviews in musculoskeletal medicine · 2026Review
- Personalized Surgical Decision-Making in Meniscal Tears: Short-Term Outcomes of Repair vs. Partial Meniscectomy in Mongolian Patients.Journal of personalized medicine · 2025Article
- Meniscal Root Repair With Centralization.Video journal of sports medicineArticle
- Meniscus extrusion after a medial meniscus root repair: Where we are and how can we solve it?Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundMeniscal extrusion has been reported to be present in >50% of knees after medial meniscus root repair. Meniscal extrusion has also been reported to be a risk factor for the progression of osteoarthritis and poorer patient-reported outcomes by impairing the ability of the meniscus to absorb hoop stress. PURPOSE: To determine whether the addition of a centralization suture to 2-tunnel transtibial root repair reduces postoperative medial meniscal extrusion in patients with type 2 posterior medial meniscus root (PMMR) tears. STUDY
designRandomized controlled trial; Level of evidence, 2.
methodsThis randomized controlled trial was performed between April 2021 and November 2024 for patients with an isolated type 2 PMMR tear. Patients undergoing PMMR repair were randomly selected to undergo transtibial repair with (treatment group) or without (control group) a centralization suture. A power analysis determined that 24 patients were necessary for the study. Magnetic resonance imaging (MRI) was performed preoperatively and at 6 months postoperatively using a high-resolution 7-T scanner. Medial meniscal extrusion was measured on coronal T2-weighted images using 2 vertical lines at the peripheral margins of the medial tibial plateau and the outermost edge of the meniscal body. Statistical analysis was performed using
resultsA total of 26 patients (21 female, 5 male) were examined; 14 patients were in the centralization group (treatment group, mean age, 50.3 years), and 12 patients were in the control group (no centralization, mean age, 56.1 years). All PMMR repair constructs were found to be intact on MRI postoperatively. Preoperatively, meniscal extrusion averaged 3.81 ± 1.16 mm for the centralization group and 3.31 ± 0.93 mm for the control group (
conclusionDespite surgically successful PMMR repair in all patients, medial meniscal extrusion was increased in 96.2% of patients at 6 months postoperatively compared to preoperatively. The addition of a centralization suture in transtibial root repair compared to isolated transtibial root repair resulted in a significantly less increase in postoperative extrusion at 6 months on MRI. REGISTRATION: NCT05088525 (ClinicalTrials.gov).
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