Evidence map›Paper›PMID 40901686›Full record

ArticleWorld journal of gastroenterology2025

Efficacy and safety of different doses of dexmedetomidine on gastrointestinal function recovery after laparoscopic colorectal surgery.

Ying Chen, Wen-Lu Tang, Chun-Tian Li, Yu Zhao, Bing Li, Lian-Ming Liao, Tian-Hua Lin, Liang-Cheng Zhang

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In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying ChenDepartment of Anaesthesiology, Fujian Medical University Union Hospital, Fuzhou 350000, Fujian Province, China.
Wen-Lu TangDepartment of Anaesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China.
Chun-Tian LiDepartment of Anaesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China.
Yu ZhaoDepartment of Anaesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China.
Bing LiDepartment of Anaesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China.
Lian-Ming LiaoDepartment of Laboratory Medicine, Fujian Medical University Union Hospital, Fuzhou 350000, Fujian Province, China.
Tian-Hua LinDepartment of Anaesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China.
Liang-Cheng ZhangDepartment of Anaesthesiology, Fujian Medical University Union Hospital, Fuzhou 350000, Fujian Province, China. zhanglc@fjmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative gastrointestinal recovery affects hospital stay time and patient's quality of life. Studies suggest that the use of dexmedetomidine during the perioperative period can promote post operational recovery of gastrointestinal function.

aimTo evaluate the efficacy and safety of different doses of dexmedetomidine on postoperative gastrointestinal function recovery after laparoscopic colorectal surgery.

methodsIn this large-sample, retrospective study, 879 patients undergoing laparoscopic colorectal surgery were categorized into three groups: A control group receiving no dexmedetomidine (

resultsMultiple linear regression analysis showed that age, gender, body mass index, American Society of Anesthesiologists classification, comorbidities and surgical site were not related to the time to first flatus (all

conclusionBoth low- and high-dose dexmedetomidine regimens enhance postoperative gastrointestinal recovery after laparoscopic colorectal surgery. The low-dose regimen demonstrates superior safety, supporting its integration into multimodal enhanced recovery pathways.

Indexed as

Colorectal SurgeryDexmedetomidineLaparoscopyPostoperative ComplicationsAdultAgedColonDose-Response Relationship, DrugFemaleHumansLength of StayMaleMiddle AgedPostoperative PeriodRecovery of FunctionRetrospective StudiesDexmedetomidineAdverse eventDexmedetomidineGastrointestinal functionLaparoscopic colorectal surgeryRetrospective study

Identifiers

PMID40901686
PMCPMC12400241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.