Evidence map›Paper›PMID 40901683›Full record

ReviewWorld journal of gastroenterology2025

Exploring the oncogenic potential of SARS-CoV-2 in the gastrointestinal tract.

Dimitrina Georgieva Miteva, Milena Gulinac, Milena Peruhova, Tsvetelina Velikova

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitrina Georgieva MitevaDepartment of Genetics, Faculty of Biology, Sofia University St. Kliment Ohridski, Sofia 1164, Bulgaria.
Milena GulinacDepartment of General and Clinical Pathology, Medical University of Plovdiv, Plovdiv 4002, Bulgaria. milena.gulinac@mu-plovdiv.bg.
Milena PeruhovaDepartment of Gastroenterology, Heart and Brain Hospital, Burgas 8000, Bulgaria.
Tsvetelina VelikovaMedical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent research has increasingly highlighted the potential oncogenic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection within the gastrointestinal tract. Growing evidence suggests that SARS-CoV-2 may contribute to the development of gastrointestinal malignancies through several mechanisms, including sustained chronic inflammation, disruption of normal cellular homeostasis, and potential viral integration into host cells. These pathological processes have the potential to dysregulate critical cellular pathways, thereby promoting cancer development in vulnerable populations. A thorough understanding of how SARS-CoV-2 interacts with the development of gastrointestinal cancer is essential for optimizing patient care and establishing comprehensive, long-term monitoring protocols. This review highlighted the pressing need for ongoing research into the complex relationship between SARS-CoV-2 infection and the risk of gastrointestinal cancer.

Indexed as

CarcinogenesisCOVID-19Gastrointestinal NeoplasmsGastrointestinal TractSARS-CoV-2HumansCoronavirus disease 2019Gastrointestinal cancerGastrointestinal tractGastrointestinal tumorsOncological potentialSevere acute respiratory syndrome coronavirus 2

Identifiers

PMID40901683
PMCPMC12400212

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.