ArticleFrontiers in medicine2025
Research status and trends of drug-coated balloons in coronary artery disease: a bibliometric analysis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Beyond the Stent ("Leave-Nothing-Behind") Drug-Coated Balloons in Acute Coronary Syndrome: A Narrative Review.Journal of clinical medicine · 2026Review
- Predictors of target lesion revascularization after paclitaxel-coated balloon angioplasty forFrontiers in cardiovascular medicine · 2026Article
- Drug-Coated Balloons and Bioresorbable Scaffolds in Spontaneous Coronary Artery Dissections.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Drug-coated balloons have emerged as a pivotal alternative to drug-eluting stents in the interventional management of coronary artery disease, particularly showing clinical advantages in the treatment of in-stent restenosis and small-vessel disease. This study provides a systematic bibliometric analysis of publication trends, research hotspots, and future directions in DCB-related CAD research from 2004 to June 2025. Methods: A total of 1,092 publications indexed in the Web of Science, Scopus, and PubMed databases were analyzed using CiteSpace, VOSviewer, and bibliometrix. Inclusion criteria were English-language papers, while case reports, conference proceedings, news articles, and duplicate publications were excluded. The analysis focused on publication trends, country/institutional contributions, author collaboration networks, journal analysis, co-citation literature, and keyword evolution. Results: Three distinct developmental phases of DCB research were identified: (1) device optimization (2004-2010), (2) clinical validation (2010-2017), and (3) application to complex lesions (2018-present). China led in publication volume ( Conclusion: DCB are now established as a standard of care for ISR (Class IA recommendation), with accumulating evidence supporting their efficacy and safety in small-vessel coronary disease. However, their application in complex lesions requires further validation through multicenter randomized controlled trials. Future research should focus on optimizing drug coating technologies, refining imaging-guided strategies, exploring new anti-proliferative drugs, and establishing more precise eligibility criteria for treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.