Evidence map›Paper›PMID 40901471›Full record

ArticleFrontiers in immunology2025

Case Report: Concurrent retinal vasculitis and optic neuritis in systemic lupus erythematosus.

Di Jin, Xun Liu, Yuwei Wang, Longjiang Fang, Weiduo Nie, Chen Li, Sheng-Guang Li, Ming Li

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Di JinDepartment of Rheumatology, Weifang People's Hospital, Weifang, Shandong, China.
Xun LiuDepartment of Ophthalmology, Weifang People's Hospital, Weifang, Shandong, China.
Yuwei WangDepartment of Emergency Internal Medicine, Weifang People's Hospital, Weifang, Shandong, China.
Longjiang FangDepartment of Radiology, Weifang People's Hospital, Weifang, Shandong, China.
Weiduo NieSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Chen LiDepartment of Dermatology, Tianjin Institute of Integrative Dermatology, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Sheng-Guang LiDepartment of Rheumatology and Immunology, Peking University International Hospital, Beijing, China.
Ming LiDepartment of Rheumatology, Weifang People's Hospital, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can affect the ocular system, with retinal vasculitis and optic neuritis being rare but serious manifestations. We present a case of a 26-year-old female with newly diagnosed SLE who developed both retinal vasculitis and optic neuritis, leading to progressive visual impairment. She was successfully treated with methylprednisolone and rituximab, achieving significant visual recovery. A review of existing literature highlights the diagnostic challenges, pathophysiology, and optimal treatment strategies for such cases. Our findings emphasize the importance of early recognition and aggressive immunosuppressive therapy in improving patient outcomes.

Indexed as

Lupus Erythematosus, SystemicOptic NeuritisRetinal VasculitisAdultFemaleHumansImmunosuppressive AgentsMethylprednisoloneRituximabImmunosuppressive AgentsMethylprednisoloneRituximabautoimmune ocular diseaseimmunosuppressive therapyoptic neuritisretinal vasculitissystemic lupus erythematosus

Identifiers

PMID40901471
PMCPMC12399518

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.