Evidence map›Paper›PMID 40901350›Full record

ArticleWorld journal of radiology2025

Developing and validating a computed tomography radiomics strategy to predict lymph node metastasis in pancreatic cancer.

Shuai Ren, Bin Qin, Marcus J Daniels, Liang Zeng, Ying Tian, Zhong-Qiu Wang

Abstract read
In one paragraph

Article in World journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Parametric mapping of dynamicCancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuai RenDepartment of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Bin QinDepartment of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Marcus J DanielsDepartment of Radiology, NYU Langone Health, New York, NY 10016, United States.
Liang ZengDepartment of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Ying TianDepartment of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
Zhong-Qiu WangDepartment of Radiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China. zhongqiuwang@njucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymph node metastasis (LNM) is a key prognostic factor in pancreatic cancer (PC). Accurate preoperative prediction of LNM remains challenging. Radiomics offers a noninvasive method to extract quantitative imaging features that may aid in predicting LNM.

aimTo investigate the potential value of a computed tomography (CT)-based radiomics model in prediction of LNM in PC.

methodsA retrospective analysis was performed on 168 pathologically confirmed PC patients who underwent contrast-enhanced-CT. Among them, 107 cases had no LNM, while 61 cases had confirmed LNM. These patients were randomly divided into a training cohort (

resultsSix radiomics features from the arterial phase and nine from the portal venous phase were selected. The Radscore model demonstrated strong predictive performance for LNM in both the training and test cohorts, with AUC values ranging from 0.86 to 0.94, sensitivity between 66.7% and 91.7%, specificity from 71.4% to 100.0%, accuracy between 78.8% and 91.1%, PPV ranging from 64.7% to 100.0%, and negative predictive value between 84.0% and 93.8%. No significant differences in AUC values were observed between the arterial and portal venous phases in either the training or test set.

conclusionThe preoperative CT-based radiomics model exhibited robust predictive capability for identifying LNM in PC.

Indexed as

Computed tomographyLymph node metastasisModel constructionPancreatic cancerRadiomics

Identifiers

PMID40901350
PMCPMC12400248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.