Evidence map›Paper›PMID 40901342›Full record

ArticleJournal of frailty, sarcopenia and falls2025

The Impact of Sarcopenic Obesity on Frailty, Cognition, and Function in Community-Dwelling Older Adults.

Le Alicia How, Xin Xiang Lee, Sarah Ann Lee Hui-En, Yao Hao Teo, Kar Cheng Goh, Li Feng Tan

Abstract read
In one paragraph

Article in Journal of frailty, sarcopenia and falls, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Le Alicia HowYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Xin Xiang LeeYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Sarah Ann Lee Hui-EnDepartment of Medicine, National University Hospital, National University Health System, Singapore.
Yao Hao TeoDepartment of Medicine, National University Hospital, National University Health System, Singapore.
Kar Cheng GohHealthy Ageing Programme, Alexandra Hospital, National University Health System, Singapore.
Li Feng TanHealthy Ageing Programme, Alexandra Hospital, National University Health System, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The impact of sarcopenic obesity (SO) on frailty, cognition, and function compared to sarcopenia and obesity alone remains unclear. This study examined SO's effects on these domains in community-dwelling older adults. Methods: We assessed 202 older adults (mean age 80.4 ±7.3 years) attending a community frailty screening clinic. Obesity was defined as BMI≥25, and sarcopenia was assessed using Asian Working Group for Sarcopenia guidelines. SO was defined as the presence of both conditions. Assessments included the Clinical Frailty Scale, Modified Barthel Index, Singapore-modified Mini-Mental State Examination, and mobility aid use. Results: Multivariate regression showed SO was significantly associated with frailty (OR 4.71), impaired function (ß: -16.53), and mobility limitations (OR 5.73). SO was also linked to cognitive impairment (OR 3.56). Sarcopenia alone was associated with frailty (OR 3.39), impaired function (ß -11.46), and mobility limitations (OR 3.32), but not cognition. Obesity alone showed no associations. SO posed higher risks for frailty, cognitive impairment, functional decline, and mobility limitations compared to sarcopenia or obesity alone. Conclusions: SO is associated with greater risks of frailty, cognitive impairment, functional decline, and mobility limitations than sarcopenia or obesity alone.

Indexed as

FrailtyObesitySarcopeniaSarcopenic obesity

Identifiers

PMID40901342
PMCPMC12401236

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.