Advances in the prevention and management of postoperative bleeding complications in pancreaticoduodenectomy: Current strategies and future directions precise.

Qian Wang, Geng-Geng Liu, Feng Pan, Jia-Yi Xu, Yan Jiao, Qing Liu, Ya-Hui Liu

Abstract readReview

In one paragraph

Review in World journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian WangDepartment of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun 130000, Jilin Province, China.

Geng-Geng LiuScience and Technology Information of Jilin Province, Changchun 130000, Jilin Province, China.

Feng PanDepartment of Radiologic Imaging, China-Japan Union Hospital of Jilin University, Changchun 130000, Jilin Province, China.

Jia-Yi XuDepartment of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun 130000, Jilin Province, China.

Yan JiaoDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

Qing LiuDepartment of Endocrinology and Metabolism, China-Japan Union Hospital of Jilin University, Changchun 130000, Jilin Province, China.

Ya-Hui LiuDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China. yahui@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative bleeding (POB) is a major complication following pancreaticoduodenectomy (PD), leading to significant morbidity and potential mortality. This minireview focuses on the prevention and management strategies for POB, synthesizing current evidence on surgical techniques, perioperative management, and postoperative interventions. Effective prevention strategies include the use of regional vessel wrapping, optimal pancreatic anastomosis, and meticulous intraoperative hemostasis. Postoperative management strategies, such as early detection using predictive models and advanced imaging, along with endovascular interventions like angiographic embolization and stent graft placement, are essential for timely intervention. Risk factors, including pancreatic texture, anticoagulation therapy, and patient comorbidities, further influence bleeding outcomes. The minireview also identifies gaps in current research and emphasizes the need for prospective randomized controlled trials to establish standardized protocols. Overall, a multidisciplinary approach combining surgical expertise, predictive analytics, and personalized care is essential to improving patient outcomes and minimizing the risk of POB following PD.

Indexed as

Angiographic embolizationEndovascular interventionsPancreaticoduodenectomyPerioperative managementPostoperative bleedingPredictive modelsPrevention strategiesRisk factorsSurgical techniques

Identifiers

PMID40901323

DOI10.5306/wjco.v16.i8.108928

PMCPMC12400236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.