Evidence map›Paper›PMID 40901139›Full record

ArticleAnnals of medicine and surgery (2012)2025

A rare presentation of subcutaneous granuloma annulare: a case report of bilateral palmar and dorsal hand nodules with successful management.

Zainab Srouji, Najem Salem, Rama Ghwich, Munir Mounla, Noura Abdul Rahman

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Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Zainab SroujiFaculty of Medicine, University of Aleppo, Aleppo, Syria.ORCID https://orcid.org/0000-0003-0002-0178
Najem SalemFaculty of Medicine, University of Aleppo, Aleppo, Syria.
Rama GhwichFaculty of Medicine, University of Aleppo, Aleppo, Syria.
Munir MounlaFaculty of Medicine, University of Aleppo, Aleppo, Syria.
Noura Abdul RahmanDepartment of Dermatology and Venereology, Faculty of Medicine, University of Aleppo, Aleppo, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: Granuloma annulare (GA) is a benign, self-limited, chronic inflammatory dermatosis predominantly affecting children and young adults. Subcutaneous granuloma annulare (SGA) is a rare variant, chiefly observed in children, characterized by firm, asymptomatic nodules typically located on the lower extremities, buttocks, or scalp. Involvement of the palms or soles is exceptionally rare. Case presentation: We report the case of a healthy teenager presenting with bilateral subcutaneous nodules on both the palmar and dorsal surfaces of the hands. Histopathological examination confirmed the diagnosis of SGA. Given the patient's aesthetic concerns, a treatment regimen of intralesional corticosteroid injections was initiated, leading to complete resolution of the lesions without recurrence during follow-up. Clinical discussion: This case represents the first documented instance of SGA involving both palmar and dorsal surfaces of the hands bilaterally in a healthy adolescent. While SGA is usually self-limited, cosmetic concerns or discomfort may necessitate therapeutic intervention. Intralesional corticosteroids have been employed with variable success in such cases. Conclusion: This case underscores the importance of considering SGA in the differential diagnosis of subcutaneous hand nodules in pediatric patients, even in atypical locations such as the palms and dorsal hands. It also highlights the efficacy of intralesional corticosteroid treatment in achieving satisfactory cosmetic outcomes without recurrence.

Indexed as

case reportcorticosteroidpalmspseudorheumatoid nodulessubcutaneous granuloma annulare

Identifiers

PMID40901139
PMCPMC12401324

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