Evidence map›Paper›PMID 40901048›Full record

ArticleJournal of extracellular biology2025

MicroRNA (miRNA) in Plasma Small Extracellular Vesicles (sEV) as Potential Early Indicators of Dairy Cow Subfertility.

Pevindu Abeysinghe, Natalie Turner, Holly Flay, Susanne Meier, Leila Cuttle, Murray D Mitchell

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pevindu AbeysingheCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health Queensland University of Technology Brisbane Queensland Australia.ORCID https://orcid.org/0000-0001-9354-352X
Natalie TurnerCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health Queensland University of Technology Brisbane Queensland Australia.ORCID https://orcid.org/0000-0002-2641-2295
Holly FlayDairyNZ Limited Hamilton New Zealand.
Susanne MeierDairyNZ Limited Hamilton New Zealand.
Leila CuttleCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health Queensland University of Technology Brisbane Queensland Australia.
Murray D MitchellCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health Queensland University of Technology Brisbane Queensland Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility-related genes represents a significant knowledge gap in understanding post-transcriptional regulatory mechanisms associated with reproductive dysfunction. Identifying subfertility markers is therefore critical to the success of fertility intervention strategies, particularly in agriculture, where sustainable farming practices are linked to overall economic performance. Here, we explore the expression patterns and association of blood plasma small extracellular vesicles (sEV)-derived miRNA with Holstein-Friesian dairy cow (

Indexed as

biological markersdifferential expressionmiRNA expressionsmall extracellular vesiclessubfertility

Identifiers

PMID40901048
PMCPMC12400363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.