ArticleJCEM case reports2025
Onset of Addison Disease in a Patient Using the Advanced Hybrid Closed-Loop MiniMed 780G: Diagnostic Challenges.
Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This case report describes a 25-year-old woman with type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease (AITD) who developed Addison disease (AD). The diagnosis was suspected due to a significant decrease in insulin requirement and recurrent hypoglycemia despite adjustments in insulin pump therapy. The patient exhibited typical clinical features of AD, including hyperpigmentation and electrolyte imbalances. Early recognition and prompt treatment are crucial in preventing a life-threatening adrenal crisis. This case highlights the importance of vigilant monitoring of T1DM patients, especially those with other autoimmune diseases, for early signs of AD. The use of continuous glucose monitoring (CGM) and insulin pump therapy can aid in the management and early detection of this complication.
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