ArticleCancer diagnosis & prognosis
Young Women With Endometrial Cancer: A Portuguese Perspective.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/Aim: Endometrial cancer (EC) is rare in premenopausal women. The aim of this study was to describe the demographic, clinical and pathological characteristics and compare survival in the light of pathological aspects of EC in young women. Patients and Methods: We performed a retrospective observational cohort study, analyzing data from 29 women up to 45 years of age diagnosed between 2003 and 2023 at our Institution. Results: The most common risk factor for EC was excess weight (75% of patients), followed by nulliparity (62.1%), diabetes mellitus (20.7%) and hypertension (17.2%). Twenty-seven patients were submitted to total hysterectomy and salpingo-oophorectomy, and additional procedures were performed for half of the patients, in particular lymph node staging (46.4%), omentectomy (17.9%) and debulking (7.1%). The majority of tumors were low-grade endometrioid (79.3%). In six cases (21.4%), synchronous ovarian cancer occurred. EC was staged FIGO I-II in 22 patients (75.9%) and 13 (46.4%) received adjuvant therapy. Univariate survival analysis showed worse progressive-free and overall survival in patients with high-grade endometrioid tumor (median survival and standard deviation of 39.8±24.2 Conclusion: Excess weight is a main risk factor for EC and the most prevalent risk factor in our study. In patients with EC, lymphovascular space invasion, poor tumor differentiation and FIGO stage III-IV are important factors associated with reduced progression-free and overall survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.