ArticleCancer diagnosis & prognosis
A Rare Case of Femur Metastasis from Brain Meningioma.
Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- When Meningioma Travels: Rare Extracranial Metastasis-Case and Review.Clinical case reports · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/Aim: Metastases of meningiomas are infrequent, and extracranial bone involvement is extremely rare. We describe a patient with femoral metastasis originating from an atypical brain meningioma. Case Report: A 55-year-old male had undergone five surgical procedures and Gamma Knife® radiosurgery for brain meningioma over five years. Four months after the final treatment he presented with spontaneous right-hip pain. Radiography showed a radiolucent lesion at the lesser trochanter; computed tomography confirmed cortical bone destruction. Positron emission tomography-computed tomography demonstrated abnormal uptake in the femur [Standardized Uptake Value (SUV) 3.3] and in residual intracranial tumor (SUV 9.9). Magnetic resonance imaging revealed low T1- and high T2-weighted signal intensities at the lesion. Open biopsy identified metastatic WHO grade II meningioma positive for epithelial membrane antigen and somatostatin receptor 2A, with a Ki-67 labelling index of approximately 10%. Wide resection of the proximal femur with endoprosthetic reconstruction was performed. Postoperatively, the patient experienced intracranial tumor recurrence and received radiation therapy. No local recurrence or additional metastases were observed during the three-year follow-up; the Enneking functional score was 60%. Conclusion: We report on an extremely rare instance of metastasis to the femur in a case of atypical brain meningioma.
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