ArticleWorld journal of methodology2025
Preoperative marking of the proximal resection margin in esophageal cancer with a surgical fiducial marker: First experiences.
Article in World journal of methodology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
backgroundNeoadjuvant therapy can reduce the size of gastroesophageal tumors to the extent that they are no longer macroscopically visible. This may increase the risk of microscopic-positive resection margins. One potential method to reduce this uncertainty could be the preoperative endoscopic marking of proximal tumor margins with BioXmark
aimTo evaluate the visibility of BioXmark
methodsThe circumference of the esophagus was endoscopically marked preoperatively with a fiducial marker in four quadrants, 5 cm proximal to the tumor. During the surgery, the surgeon's proposed proximal resection line was marked. Next, an ultrasound probe was used to identify the previously placed fiducial markers, and its placement was marked. The difference between the surgeon's proposed resection line and the fiducial marker was measured intraoperatively and subsequently examined with respect to the resection margin and status.
resultsBioXmark
conclusionExcellent technical success with the implantation of the fiducial surgical marker was achieved, but limited intraoperative visibility on ultrasound was achieved. Further studies are required to optimize its clinical application.
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