Evidence map›Paper›PMID 40900806›Full record

ArticleFrontiers in oncology2025

Familial Carney complex with embolic ischemic stroke: a case report and literature review.

Tingting Luo, Mengxing Yin, Lijin Li, Mengjiao Sun, Zhen Li, Pengge Li, Mengmeng Liu, Xinxin Sun, Zhanyi Wu, Yifan Liu and 4 more

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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Tingting Luo *Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengxing Yin *Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lijin LiDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengjiao SunDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhen LiDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Pengge LiDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mengmeng LiuDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xinxin SunDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhanyi WuDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yifan LiuDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lulu ZhangDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhiyao WangDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Suyun HouDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shaohua HuaDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carney complex (CNC) is a rare autosomal dominant multiple neoplasia syndrome characterized by cutaneous and mucosal pigmented lesions, cardiac myxomas, and various endocrine and non-endocrine tumors. Methods: We report a familial case of CNC presenting initially with embolic ischemic stroke. Comprehensive clinical evaluation, imaging studies, histopathological examination, and genetic analysis were performed on the proband and family members, with a literature review summarizing the clinical features of CNC. Results: A pathogenic Conclusions: CNC should be suspected in young patients presenting with cardiac myxoma and stroke. Clinicians should maintain high vigilance for patients with multi-system symptoms and complex family histories. Comprehensive family history assessment and genetic testing facilitate early diagnosis of CNC.

Indexed as

Carney complexembolic ischemic strokemultiple endocrine neoplasiamyxomaPRKAR1A

Identifiers

PMID40900806
PMCPMC12399879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.