Evidence map›Paper›PMID 40900773›Full record

ReviewWorld journal of gastroenterology2025

Epiploic appendagitis: An overlooked cause of acute abdominal pain.

Yasser El-Sawaf, Salman Alzayani, Nermin K Saeed, Adel S Bediwy, Reem Elbeltagi, Khaldoon Al-Roomi, Mohammed Al-Beltagi

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasser El-SawafDepartment of Tropical Medicine, Faculty of Medicine, Tanta University, Tanta 31527, Alghrabia, Egypt.
Salman AlzayaniDepartment of Family and Community Medicine, College of Medicine and Health Sciences, Arabian Gulf University, Manama 26671, Bahrain.
Nermin K SaeedMedical Microbiology Section, Department of Pathology, Salmaniya Medical Complex, ‎Governmental Hospitals, Manama 26671, Bahrain.
Adel S BediwyDepartment of Pulmonology, Faculty of Medicine, Tanta University, Tanta 31527, Alghrabia, Egypt.
Reem ElbeltagiDepartment of Medicine, Royal College of Surgeons in Ireland, Medical University of Bahrain, Busaiteen 15503, Muharraq, Bahrain.
Khaldoon Al-RoomiDepartment of Family and Community Medicine, College of Medicine and Health Sciences, Arabian Gulf University, Manama 26671, Bahrain.
Mohammed Al-BeltagiDepartment of Pediatrics, Faculty of Medicine, Tanta University, Tanta 31511, Algharbia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpiploic appendagitis is a rare, often underrecognized cause of acute abdominal pain. Misdiagnosis can lead to unnecessary hospitalization, antibiotic use, or surgical intervention. Advances in imaging have improved the recognition of this self-limiting condition, but clinical awareness remains critical.

aimTo provide a comprehensive update on the epidemiology, anatomy, pathogenesis, clinical presentation, diagnostic strategies, differential diagnosis, and management of epiploic appendagitis, emphasizing its distinguishing features from other causes of acute abdomen.

methodsA review of the literature was conducted, focusing on the clinical characteristics, imaging findings, differential diagnoses, and evidence-based management strategies for epiploic appendagitis.

resultsEpiploic appendagitis typically presents with acute, localized, non-radiating abdominal pain without significant systemic symptoms. Diagnosis is heavily reliant on imaging, with computed tomography (CT) being the gold standard. Hallmark CT findings include a small, fat-density ovoid lesion adjacent to the colon, with the usual characteristic ring and dot signs. Differential diagnoses include mainly diverticulitis, appendicitis, omental infarction, and many other causes. Management is predominantly conservative with nonsteroidal anti-inflammatory drugs and observation, reserving surgical intervention for rare, complicated cases.

conclusionRecognizing the clinical and imaging features of epiploic appendagitis is essential to avoid unnecessary interventions. Increased clinician awareness, coupled with judicious use of imaging, facilitates timely diagnosis and appropriate management, ensuring optimal patient outcomes.

Indexed as

Abdomen, AcuteColitisAnti-Inflammatory Agents, Non-SteroidalAppendicitisColonDiagnosis, DifferentialDiagnostic ErrorsHumansTomography, X-Ray ComputedAnti-Inflammatory Agents, Non-SteroidalAbdominal fat necrosisAcute abdominal painAppendices epiploicae inflammationDivericulitisEpiploic appendagitisEpiploic appendicitis

Identifiers

PMID40900773
PMCPMC12400226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.