Evidence map›Paper›PMID 40900712›Full record

ArticleFrontiers in public health2025

Association between occupational ionizing radiation exposure duration and the increased risk of dyslipidemia: evidence from a large group of radiation workers.

Meimei Zhong, Xiaowen Wang, Qifeng Li, Zhijia Wu, Xiangyuan Huang, Xinyue Li, Yiqing Lian, Yingyi Peng, Zhiqiang Li, Zhifang Liu and 14 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Meimei Zhong *Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Xiaowen Wang *Center for Public Health and Epidemic Preparedness and Response, School of Public Health, Peking University Health Science Center, Beijing, China.
Qifeng LiGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Zhijia WuGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Xiangyuan HuangGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Xinyue LiGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Yiqing LianGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Yingyi PengGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Zhiqiang LiGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Zhifang LiuGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Qia WangGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Yajun GongGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Peixia HuGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Xiaoyong LiuGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Shuming ZhuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Shaomin WuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Fangfang ZengDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Yiru QinGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Qiying NongGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Jinhan WangTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Yeqing GuTianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Yongshun HuangGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Wangjian ZhangDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Na ZhaoGuangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although radiation workers' exposure levels consistently remained below established safety thresholds, accumulating evidence demonstrates that chronic low-dose ionizing radiation exposure may still pose significant health risks to humans. We aimed to explore the relationship between the years of low-dose radiation work and dyslipidemia. Methods: We collected occupational and physical examination data of 10,338 radiation workers from 1,200 workplaces during 2019-2020 in Guangdong Province, China. After controlling for social demographic and health behavior confounders, we used a mixed-effects model to assess the association of ionizing radiation exposure duration with blood lipid biomarkers as well as the prevalence of dyslipidemia. We further comprehensively evaluated the modifying effects of various demographic characteristics, health behavior factors, and air pollutant concentrations. Results: We found that participants with prolonged ionizing radiation exposure tended to have 8-40% higher levels of total cholesterol (TC) compared to those with < 10 years of exposure. The estimates were 9-23% for triglycerides (TG) and 5-26% for low-density lipoprotein cholesterol (LDL-C). Similar disparities were observed for the prevalence of overall dyslipidemia, abnormal TC or TG, hypercholesterolemia, hypertriglyceridemia, and high Conclusion: These findings suggest a deleterious effect of prolonged ionizing radiation exposure on lipid metabolism, with certain groups of workers being particularly vulnerable.

Indexed as

DyslipidemiasOccupational ExposureRadiation ExposureRadiation, IonizingAdultChinaFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsTime Factorsdyslipidemiaionizing radiationlipid biomarkersmixed-effect modelradiation worker

Identifiers

PMID40900712
PMCPMC12401101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.