Evidence map›Paper›PMID 40900520›Full record

ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2025

Outbreak of infections by Mycobacterium abscessus subsp. abscessus associated with cosmetic surgeries in the Brazil/Paraguay border: a binational cohort study, 2021-2022.

Mateus de Paula von Glehn, Griselda Salcedo, Talita Gomes da Silva Batista, Lorena Elizabeth Romero Caballero, Carlos Henrique Michiles Frank, Eunice Atsuko Totumi Cunha, Aline Schio de Souza, Camile de Moraes, Igor Gonçalves Ribeiro

Abstract read
In one paragraph

Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mateus de Paula von GlehnSecretaria de Estado da Saúde do Distrito Federal, Brasília, DF, Brazil.ORCID 0000-0003-3609-251X
Griselda SalcedoMinisterio de Salud Publica y Bienestar Social, Field Epidemiology Training Program, Asunción, Paraguai.ORCID 0009-0008-4283-7278
Talita Gomes da Silva BatistaMinistério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do SUS, Brasília, DF, Brazil.ORCID 0009-0000-7572-6947
Lorena Elizabeth Romero CaballeroMinisterio de Salud Publica y Bienestar Social, Field Epidemiology Training Program, Asunción, Paraguai.ORCID 0000-0002-7466-0357
Carlos Henrique Michiles FrankMinistério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do SUS, Brasília, DF, Brazil.ORCID 0000-0002-4202-2799
Eunice Atsuko Totumi CunhaLaboratório Central de Saúde Pública, Campo Grande, MS, Brazil.ORCID 0000-0002-5700-9044
Aline Schio de SouzaSecretaria de Estado de Saúde do Mato Grosso do Sul, Campo Grande, MS, Brazil.ORCID 0009-0008-2937-4870
Camile de MoraesFundação Oswaldo Cruz, Núcleo de Epidemiologia e Vigilância em Saúde, Brasília, DF, Brazil.ORCID 0000-0003-4789-0429
Igor Gonçalves RibeiroMinistério da Saúde, Programa de Treinamento em Epidemiologia Aplicada aos Serviços do SUS, Brasília, DF, Brazil.ORCID 0000-0002-4971-9484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Report on a field investigation into the outbreak of skin infections by Mycobacterium abscessus subsp. abscessus following cosmetic procedures. Methods: A retrospective cohort study was conducted using secondary data from the Epidemiology Program Applied to SUS Services (EpiSUS) about the investigation conducted in 2022, in partnership with Paraguay's Field Epidemiology Training Program. Clinical, laboratory, and environmental information and surgical records were analyzed to characterize the cases, define the exposed population, and analyze the risk. Relative risk (RR) was estimated with a 95% confidence interval (95%CI) and Fisher's exact test was used for statistical evaluation. Results: Of the 108 individuals who underwent surgery in the period investigated, 10 became ill. Relative risk of illness was 6.50 (95%CI 2.28; 18.49; p-value 0.003) for surgeries performed in the critical period (December to January) and 10.29 (95%CI 1.37; 77.19; p-value 0.004) for lipoabdominoplasty. Conclusion: Mycobacterium abscessus subsp. abscessus outbreak occurred among women undergoing cosmetic surgeries performed by the same professional in a hospital in Paraguay, with a higher risk associated with a specific period and type of procedure. Our findings highlight the importance of health surveillance in bordering regions and international cooperation in response to cross-border events. Educational, regulatory, and inspection strategies targeting medical tourism are essential to prevent new events.

Indexed as

Mycobacterium Infections, NontuberculousPlastic Surgery ProceduresSurgery, PlasticSurgical Wound InfectionBrazilCohort StudiesDisease OutbreaksHumansInternationalityMycobacterium abscessusParaguayPostoperative ComplicationsRetrospective Studies

Identifiers

PMID40900520
PMCPMC12435886

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.