ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Prognostic value of inflammatory and radiologic markers in pediatric bell's palsy: a retrospective study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the prognostic significance of inflammatory markers, computed tomography (CT)-based facial nerve measurements, and clinical parameters in pediatric patients with Bell's palsy.
methodsIn this retrospective study, 136 patients aged 4-18 years diagnosed with Bell's palsy were evaluated. Clinical data included age, sex, affected side, initial House-Brackmann (HB) grade, recovery grades at one month and final follow-up, presence of pain, and treatment timing. Inflammatory markers-mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein-to-albumin ratio (CAR)- were calculated from laboratory data obtained at admission. Facial nerve-to-facial canal (FN/FC) ratios were measured via CT in five regions. The control group included 70 age-matched children with normal CT scans obtained for non-specific complaints such as headache. Recovery was categorized as full (HB 1), partial (improved but not grade 1), or poor.
resultsInitial HB grade was significantly correlated with both one-month (r = 0.67, p < 0.001) and final recovery (r = 0.33, p < 0.001). CAR was weakly correlated with one-month recovery (r = 0.224, p = 0.0089) but not long-term outcome. MPV, NLR, and PLR showed no significant prognostic value. FN/FC ratios were significantly higher in the labyrinthine, geniculate, and tympanic regions on the paralyzed side compared to both the control group and non-paralyzed side. However, no correlations were found between FN/FC ratios and recovery. A moderate correlation was observed between initial HB grade and tympanic FN/FC ratio (r = 0.321, p = 0.001).
conclusionInitial clinical severity best predicts recovery in pediatric Bell's palsy. Inflammatory and radiologic parameters offer limited prognostic value and warrant cautious interpretation.
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