Evidence map›Paper›PMID 40900287›Full record

ReviewStem cell reviews and reports2025

Veterinary Regenerative Medicine: The Evolving Role of Stem Cell-Based Therapies.

Ananya Aeri, Madhavi Gorla, G Taru Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ananya AeriDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, 500032, Telangana, India.
Madhavi GorlaDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, 500032, Telangana, India.
G Taru SharmaDBT-National Institute of Animal Biotechnology (NIAB), Hyderabad, 500032, Telangana, India. tarusharma@niab.org.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Veterinary medicine has witnessed a paradigm shift in recent past with the preference to use mesenchymal stem cells (MSCs) for livestock and companion animal therapeutics. MSCs made remarkable developments in treating complex clinical conditions, otherwise difficult to treat with routine medications such as musculoskeletal injuries, osteoarthritis, tendon and ligament damage, degenerative diseases, gastritis, endometritis, diabetes mellitus, and ocular diseases, offering new hope for veterinary practitioners and animal caregivers. This review is divided into two sections: The first part explores recent advancements in veterinary medicine using MSCs, mainly focusing on their sources, administration methods, therapeutic mechanisms, and clinical applications. Whereas, the second section highlights the emerging trends in advanced therapeutic strategies, including MSC and its derived cell-free therapies, with or without scaffolds, offering less invasive and more targeted treatments. Many studies show that MSCs from different sources exhibit unique regenerative and immunomodulatory properties, enabling more effective and better-quality tissue repair with appreciable inflammation control. However, despite the aforementioned promises, some challenges still remain, including the need for standardized therapy protocols, including the doses and a good number of replicates for long-term clinical trials to ensure safety and efficacy. This review covers a comprehensive overview of the current landscape of stem cell research and explores its translational potential in the latest developments shaping the future of veterinary regenerative medicine, especially using mesenchymal stem cells.

Indexed as

Cell- and Tissue-Based TherapyMesenchymal Stem CellsMesenchymal Stem Cell TransplantationRegenerative MedicineVeterinary MedicineAnimalsHumansAnd ScaffoldsCell-free therapyImmunomodulationMesenchymal stem cells (MSCs)Osteogenic differentiationTherapeutic applicationVeterinary regenerative medicine

Identifiers

PMID40900287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.