Evidence map›Paper›PMID 40900247›Full record

SynthesisObesity surgery2025

Refeeding Syndrome After Metabolic and Bariatric Surgery: A Systematic Review of the Literature.

Konstantinos Katsikas Triantafyllidis, Panagiotis Giannos, Georgios Geropoulos, Dimitra Stathi, Konstantinos Kechagias, Gerard McCabe, James Lucocq, Andrew G Robertson

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Konstantinos Katsikas TriantafyllidisHomerton University Hospital, London, United Kingdom.
Panagiotis GiannosSociety of Meta-Research and Biomedical innovation, London, United Kingdom.
Georgios GeropoulosAddenbrooke's Hospital, Cambridge, United Kingdom.
Dimitra StathiSociety of Meta-Research and Biomedical innovation, London, United Kingdom.
Konstantinos KechagiasSociety of Meta-Research and Biomedical innovation, London, United Kingdom.
Gerard McCabeEdinburgh Royal Infirmary, Edinburgh, United Kingdom. g.mccabe1991@gmail.com.
James LucocqEdinburgh Royal Infirmary, Edinburgh, United Kingdom.
Andrew G RobertsonEdinburgh Royal Infirmary, Edinburgh, United Kingdom. andrew.robertson6@nhs.scot.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRefeeding syndrome (RFS) is defined as a set of metabolic and electrolyte abnormalities after nutrition initiation following prolonged starvation or protracted vomiting. Metabolic and bariatric surgery (MBS) and the associated rapid weight loss have been proposed as potential triggering factors for RFS.

objectiveThis study aimed to examine the currently available literature and provide an overview of the reported cases of RFS in patients who underwent metabolic and bariatric surgery.

methodWe performed a systematic screening of Embase, Medline, and Scopus until June 2024. The review was conducted according to PRISMA guidelines.

resultsWe identified a total of nine patients with RFS who had a history of metabolic and bariatric surgery with a median age of 38 years (IQR 32-44). Five participants (55.5%) were females, and two were males (22.2%). Adjustable gastric banding was the main bariatric procedure performed in almost half of the patients (44.4%, 4/9) followed by Roux-en-Y gastric bypass (22.2%, 2/9). Post-operatively, all patients experienced weight loss that ranged from 29.7% to 78.1% total percentage weight loss. The most common symptoms included vomiting (44.4%, 4/9) and abdominal pain (22.2%, 2/9). Most patients (66.6%, 6/9) received vitamin supplementation, followed by electrolyte replacement (55.5%, 5/9). Most patients (88.8%, 8/9) improved, and one patient died (11%, 1/9).

conclusionRefeeding syndrome is a rarely reported complication after metabolic and bariatric surgery, but as the frequency of MBS increases, RFS is expected to become more common. Clinical awareness among bariatric and metabolic specialists is important for the identification of high-risk individuals as well as for the early diagnosis and adequate management of patients with RFS.

Indexed as

Bariatric SurgeryObesity, MorbidPostoperative ComplicationsRefeeding SyndromeAdultFemaleHumansMaleWeight LossMetabolic and bariatric surgeryNutritionRefeeding syndromeSleeve gastrectomyWeight loss

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.