Evidence map›Paper›PMID 40900188›Full record

ArticleAIDS education and prevention : official publication of the International Society for AIDS Education2025

Lessons Learned From a Trial of a Bilingual Community-Based Peer Navigation And mHealth Intervention to Address HIV, STI, HCV, and Mpox Inequities Among GBQMSM and Transgender and Nonbinary Persons in Appalachia.

Lilli Mann-Jackson, Jorge Alonzo, John W Chaffin, Sandy K Aguilar-Palma, Amanda E Tanner, David M Kline, Ana D Sucaldito, Jeanette M Stafford, Mohammed Sheikh Eldin Jibriel, Tamar Goldenberg and 5 more

Abstract read
In one paragraph

Article in AIDS education and prevention : official publication of the International Society for AIDS Education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lilli Mann-JacksonDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Jorge AlonzoDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
John W ChaffinWestern North Carolina AIDS Project, Asheville, North Carolina.
Sandy K Aguilar-PalmaDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Amanda E TannerDepartment of Public Health Education, University of North Carolina Greensboro, Greensboro, North Carolina.
David M KlineDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Ana D SucalditoDepartment of Public Health Education, University of North Carolina Greensboro, Greensboro, North Carolina.
Jeanette M StaffordDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Mohammed Sheikh Eldin JibrielDepartment of Public Health Education, University of North Carolina Greensboro, Greensboro, North Carolina.
Tamar GoldenbergDepartment of Public Health Education, University of North Carolina Greensboro, Greensboro, North Carolina.
Laurie P RussellDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Antonio Del ToroWestern North Carolina AIDS Project, Asheville, North Carolina.
Peggy H WeilWestern North Carolina AIDS Project, Asheville, North Carolina.
Aimee M WilkinDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Scott D RhodesDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Funding

Harnessing the power of peer navigation and mHealth to reduce health disparities in AppalachiaR01NR019512 · NINR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RHODES, SCOTT D, TANNER, AMANDA E · 2020 to 2024
$2.3M
NINR NIH HHS R01 NR019512
6 · The paper itself

Abstract

Our community-based participatory research partnership developed and tested the bilingual Appalachian Access Project, a peer navigation and mHealth intervention designed to promote HIV, sexually transmitted infection, hepatitis C virus, and mpox prevention and care among gay, bisexual, queer, and other men who have sex with men and transgender and nonbinary persons in Appalachia and to support medically supervised gender-affirming hormone therapy (GAHT) access among those desiring it. Although the intervention did not achieve its intended behavioral outcomes (e.g., increased use of HIV testing, preexposure prophylaxis [PrEP], HIV care, and GAHT), we identified ten critical lessons for future intervention research, including needs for: increased contact between study team members and peer navigators, more streamlined health outcome priorities, minimum intervention dose requirements for peer navigators, formal group activities, smaller catchment areas, and provider and organizational capacity-building interventions. Deeper understanding of intervention implementation can strengthen future efforts to reduce health disparities in Appalachia.

Indexed as

Hepatitis CHIV InfectionsMpox, MonkeypoxPeer GroupSexual and Gender MinoritiesSexually Transmitted DiseasesTransgender PersonsAdultAppalachian RegionCommunity-Based Participatory ResearchFemaleHumansMaleMiddle AgedTelemedicineAppalachiaHCVHIVLGBTQ+mpoxSTIs

Identifiers

PMID40900188
PMCPMC12820806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.