Evidence map›Paper›PMID 40900163›Full record

ArticleEuropean journal of pediatrics2025

Enhancement of postural control and upper limb function following selective dorsal rhizotomy: a retrospectively registered study.

Pasquale Cardellicchio, Marta Bertamino, Anna Bruna Ronchetti, Ludovica Primavera, Luca Doglio, Alessia Aiello, Annalisa Calcagno, Marina Usai, Maria Grazia Calevo, Marco Pavanello and 1 more

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Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pasquale CardellicchioPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy. pasquale.cardellicchio@gaslini.org.
Marta BertaminoPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Anna Bruna RonchettiPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Ludovica PrimaveraPsychology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Luca DoglioPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Alessia AielloPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Annalisa CalcagnoPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Marina UsaiPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Maria Grazia CalevoStatistic and Epidemiology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Marco PavanelloNeurosurgery Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Chiara TacchinoPhysical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Funding

The Italian Ministry of Health, 5x1000 project n. 5M-2019-23680415
6 · The paper itself

Abstract

Cerebral palsy is the most common pediatric disability, characterized by a spectrum of permanent disorders that hinder movement, posture, and overall activity, causing long-term functional limitations. For those unresponsive or unsuitable to conventional treatments, neurosurgical interventions such as selective dorsal rhizotomy or intrathecal baclofen may be considered. Selective dorsal rhizotomy (SDR) aims to reduce lower limb spasticity while preserving sensory and sphincteric functions. Despite its established effectiveness in the control of lower limb increased muscle tone, its impacts on the upper limb motor performance and the trunk control require further investigations. This study aims to systematically assess changes in neck, trunk, and upper limb functionality following Selective Dorsal Rhizotomy in children with cerebral palsy, highlighting the improvements and the timeline of recovery after surgery.

conclusionsSelective dorsal rhizotomy improvements achieved are significant especially in the early post-surgical phase and already detectable three months after surgery and involved also a reduction in both upper limb function and trunk misalignment. Determining post-operative improvements and recovery times can help maximize post-operative outcomes through appropriate rehabilitation therapies. WHAT IS KNOWN: • Selective dorsal rhizotomy (SDR) aims to reduce lower limb spasticity while preserving sensory and sphincteric functions, but limited research exists regarding the impact of SDR on the improvement of upper limb function and trunk control. WHAT IS NEW: • This study reveals key insights into changes in neck, trunk, and upper limb function post-SDR in children with CP, identifying which parameters improve, and the timeline of these improvements. Our findings suggest how age at surgery have an impact on the short-term improvement on the upper-limb movements, shedding new light on the importance of fine-tuning appropriate rehabilitation protocols.

Indexed as

Cerebral PalsyMuscle SpasticityPostural BalanceRhizotomyUpper ExtremityAdolescentChildChild, PreschoolFemaleHumansMaleRecovery of FunctionRetrospective StudiesTreatment OutcomeCerebral palsyGross Motor Functional MeasureLevel Sitting ScaleMelbourne Assessment ScaleSelective dorsal rhizotomyUpper limb and trunk control

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.