Evidence map›Paper›PMID 40900100›Full record

ArticleEmerging microbes & infections2025

Characterization of the first detected Avian Influenza A(H9N2) human case in Ghana.

Ivy Asantewaa Asante, Nana Afia Asante-Ntim, Abigail Akua Abankwa, Obed Bangdome Ofori, Linda Boatemaa, Lorreta Kwasah, Joseph Ahia Quarcoo, Joseph A Nyarko, Gifty Mawuli Sarpong, Stephen Ofori Nyarko and 19 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Ivy Asantewaa AsanteNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Nana Afia Asante-NtimNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Abigail Akua AbankwaNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Obed Bangdome OforiDisease Surveillance Department, Ghana Health Service, Accra, Ghana.
Linda BoatemaaNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Lorreta KwasahNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Joseph Ahia QuarcooNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Joseph A NyarkoNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Gifty Mawuli SarpongNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Stephen Ofori NyarkoNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Vanessa MagnusenNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Jennifer WutsikaNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Samuel AgoNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Esinam Aku Apefa AmenuvorNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Juliet WorduiNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Roberta TackieNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Ama Nyansema Sekyi-YorkeNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Cecilia TakyiNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Innocent DokuNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
William Kwabena AmpofoNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Mildred Adusei-PokuNoguchi Memorial Institute for Medical Research (NMIMR), University of Ghana, Accra, Ghana.
Patrick DawsonInfluenza Division, US-CDC, Atlanta, GA, USA.
Ndahwouh Talla NzussouoInfluenza Division, US-CDC, Atlanta, GA, USA.
Daniel OwusuInfluenza Division, US-CDC, Atlanta, GA, USA.
Shirley Nimo-PaintsilU. S. Naval Medical Research Unit-EURAFCENT, Ghana Detachment, Accra, Ghana.
Naiki AttramU. S. Naval Medical Research Unit-EURAFCENT, Ghana Detachment, Accra, Ghana.
Franklin Asiedu BekoePublic Health Division, Ghana Health Service, Accra, Ghana.
Dennis Odai LaryeaDisease Surveillance Department, Ghana Health Service, Accra, Ghana.
Myrna CharlesInfluenza Division, US-CDC, Atlanta, GA, USA.

Funding

NCIRD CDC HHS H23 IP000909
6 · The paper itself

Abstract

Avian influenza A(H9N2) has been circulating in poultry across Asia, the Middle East, and Africa, posing human health risks. In Ghana, it has co-circulated among poultry with influenza A (H5N1). This report describes Ghana's first confirmed human case of avian influenza A(H9N2) virus infection in a two-year-old boy from Upper East Region, identified through active respiratory surveillance. Molecular and genomic analyses confirmed the virus was of the G1 lineage, closely related to other West African strains, with mammalian adaptive mutations known to increase human infection potential. The child experienced mild symptoms, received outpatient care, and recovered. Health authorities conducted epidemiological investigations. No source was identified for the child's infection; no additional human infections were detected. This case highlights the importance of robust avian influenza surveillance in animals and humans, particularly in regions with human-animal interactions. It underscores the importance of national and global collaboration using a One Health approach to detect and prevent zoonotic spillovers and potential pandemics.

Indexed as

Influenza A Virus, H9N2 SubtypeInfluenza, HumanInfluenza in BirdsAnimalsChild, PreschoolGhanaHumansMalePhylogenyPoultryAvian influenzacross over eventGhanahumanOne-Healthsurveillance

Identifiers

PMID40900100
PMCPMC12502110

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.