Evidence map›Paper›PMID 40899974›Full record

ArticleThe International journal of social psychiatry2026

Delivery and delay of guideline pharmacological, psychological, and social interventions for adults with complex psychosis in Dutch inpatient rehabilitation units: A retrospective study.

Thijs J Burger, Hans J de Haas, Robin M Van Eck, Martijn Kikkert, Frederike Schirmbeck, Astrid Vellinga, Lieuwe de Haan, Mariken B de Koning

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Article in The International journal of social psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Thijs J BurgerArkin, Institute for Mental Health, Amsterdam, The Netherlands.ORCID 0000-0001-6955-2725
Hans J de HaasArkin, Institute for Mental Health, Amsterdam, The Netherlands.
Robin M Van EckAmsterdam University Medical Centre, Department of Psychiatry, Amsterdam, The Netherlands.ORCID 0000-0002-0381-8559
Martijn KikkertArkin, Institute for Mental Health, Amsterdam, The Netherlands.
Frederike SchirmbeckCentral Institute of Mental Health, Department of Public Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Astrid VellingaArkin, Institute for Mental Health, Amsterdam, The Netherlands.
Lieuwe de HaanArkin, Institute for Mental Health, Amsterdam, The Netherlands.
Mariken B de KoningArkin, Institute for Mental Health, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with complex psychosis admitted to inpatient mental health rehabilitation units (IMRU) constitute a low volume, high need, high cost group with a complicated recovery process.

aimsTo generate hypotheses regarding successful delivery of guideline care to patients with complex psychosis in IMRUs, based on clinical profiles and (historical) patterns of care delivery.

methodA retrospective passive consent chart study of patients with complex psychosis in IMRUs in The Netherlands, mapping sociodemographic and clinical profiles, care trajectories and delivery of pharmacological (focusing on clozapine delay), psychological and social guideline interventions. We assessed relationships between non-delivery of psychological and social interventions, delay in clozapine treatment, and current symptom severity.

resultsThe 62 included patients had a mean illness duration of 21.6 years (

conclusionsFor some people with complex psychosis, clozapine treatment and psychosocial interventions may only materialize in specialized, long term, high structure settings offering continuity of care. Support in developing day activities may present a pathway to collaborative engagement. Early identification of those in need remains a challenge.

Indexed as

Antipsychotic AgentsPsychiatric RehabilitationPsychotic DisordersSchizophreniaAdultClozapineFemaleHumansInpatientsMaleMiddle AgedNetherlandsPractice Guidelines as TopicRetrospective StudiesTime-to-TreatmentAntipsychotic AgentsClozapineclozapine treatmentcomplex psychosisinpatient mental health rehabilitation unitinstability of living environmentpsychosocial interventionssevere mental illness

Identifiers

PMID40899974
PMCPMC12946213

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