Evidence map›Paper›PMID 40899829›Full record

ArticleJournal of bacteriology2025

Role of thioredoxin reductase (TrxB) in oxidative stress response of

Matthew Higgs, Zhuo Ma, Anthony Centone, Chandra Shekhar Bakshi, Meenakshi Malik

Abstract read
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew Higgs *Department of Life Sciences, Albany College of Pharmacy and Health Sciences, Albany, New York, USA.ORCID 0000-0002-5460-4980
Zhuo Ma *Department of Life Sciences, Albany College of Pharmacy and Health Sciences, Albany, New York, USA.
Anthony CentoneDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Chandra Shekhar BakshiDepartment of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.ORCID 0000-0001-5459-3225
Meenakshi MalikDepartment of Life Sciences, Albany College of Pharmacy and Health Sciences, Albany, New York, USA.ORCID 0000-0003-0051-4485

Funding

Repression of Inflammasome by Francisella tularensisR15AI107698 · NIAID · ALBANY COLLEGE OF PHARMACY · PI MALIK, MEENAKSHI · 2013 to 2024
$1.9M
NIAID NIH HHS R15 AI107698NIH HHS R15AI107698NIH HHS R21AI51277
6 · The paper itself

Abstract

IMPORTANCE: This study elucidates the function of the

Indexed as

Bacterial ProteinsBacterial VaccinesFrancisella tularensisOxidative StressThioredoxin-Disulfide ReductaseAnimalsAnti-Bacterial AgentsAuranofinGene Expression Regulation, BacterialMacrophagesMiceThioredoxinsTularemiaVaccines, AttenuatedAnti-Bacterial AgentsAuranofinBacterial ProteinsBacterial VaccinesThioredoxin-Disulfide ReductaseThioredoxinsVaccines, Attenuatedantibiotic resistanceauranofinFrancisellaintramacrophage survivaloxidative stressthioredoxin reductase

Identifiers

PMID40899829
PMCPMC12478593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.