ArticleJournal of the International Society of Sports Nutrition2025
Chronic low water intake is associated with altered exercise-induced oxidative stress and immune cell responses: a cross-sectional study.
Article in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHydration status plays a critical role in modulating oxidative stress during exercise, which can influence physical performance and recovery. While the acute effects of hydration on exercise-induced oxidative stress are well-documented, the long-term impact of chronic water intake remains poorly understood. Therefore, this study aimed to investigate the relationship between chronic low water intake and exercise-induced oxidative stress, as well as changes in the phenotypic composition of peripheral immune cells.
methodsWe assessed the usual plain water intake of the participants (
resultsAt baseline, the LOW group showed higher concentrations of serum ROMs than the HIGH group (
conclusionHabitual low water intake was associated with elevated concentrations of free radical by-products in the resting state and impaired antioxidant capacity during acute exercise stress. In response to exercise stress, impaired redox balance in low-water drinkers resulted in accelerated cellular damage and increased myeloid cell recruitment. These findings highlight the importance of maintaining adequate habitual water intake to cope with exercise-induced oxidative stress and prevent excessive cellular stress responses. CLINICAL
trial registrationRegistered at the Clinical Research Information Service (CRIS) on 12 April 2019 (Registry No. KCT0003763).
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