Evidence map›Paper›PMID 40899420›Full record

ArticleThe Laryngoscope2026

Sterile Nasal Septal Abscess in Ulcerative Colitis With Crypt Abscess-Like Neutrophilic Infiltration.

Masakazu Murayama, Yoshihito Tanaka, Tomoyuki Yokose, Toshikazu Shimane

Abstract readCase Reports
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Masakazu MurayamaDepartment of Otolaryngology - Head and Neck Surgery, School of Medicine, Showa Medical University, Tokyo, Japan.ORCID 0009-0003-6871-1108
Yoshihito TanakaDepartment of Otolaryngology - Head and Neck Surgery, Odawara Municipal Hospital, Odawara, Japan.
Tomoyuki YokoseDepartment of Pathology, Odawara Municipal Hospital, Odawara, Japan.
Toshikazu ShimaneDepartment of Otolaryngology - Head and Neck Surgery, School of Medicine, Showa Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of a sterile nasal septal abscess (NSA) occurring as an extraintestinal manifestation of ulcerative colitis (UC), accompanied by a novel histopathologic finding. A 40-year-old woman with relapsed UC presented with nasal swelling, purulent discharge, hematochezia, and skin lesions. Computed tomography revealed an anterior NSA, and emergent endoscopic drainage was performed. Despite broad-spectrum antibiotics, her condition worsened, and corticosteroids were initiated. Histopathologic analysis of the nasal mucosa demonstrated crypt abscess-like neutrophilic infiltration within glandular structures, resembling colonic crypt abscesses in active UC. Cultures were negative, and her condition improved with immunosuppressive therapy. To our knowledge, this is the first reported case of a sterile NSA with crypt abscess-like structures in the nasal mucosa, expanding the histopathologic spectrum of sinonasal manifestations in UC. Early recognition and prompt immunosuppressive therapy are essential to avoid complications such as saddle nose deformity.

Indexed as

AbscessColitis, UlcerativeNasal SeptumNeutrophil InfiltrationNose DiseasesAdultFemaleHumansTomography, X-Ray Computednasal septal abscessneutrophilic infiltrationpyoderma gangrenosumulcerative colitis

Identifiers

PMID40899420
PMCPMC12793958

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.