Evidence map›Paper›PMID 40899269›Full record

ArticleCirculation. Heart failure2025

Integrative Multiomics for Prognostic Assessment in Pulmonary Arterial Hypertension.

Hongyang Pi, Samuel G Rayner, Ali Shojaie, Sina A Gharib, Peter J Leary, Lu Xia

Abstract readLetter
In one paragraph

Article in Circulation. Heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongyang PiDepartment of Medicine (H.P., S.G.R., S.A.G., P.J.L.), University of Washington, Seattle.ORCID 0000-0002-6963-3354
Samuel G RaynerDepartment of Medicine (H.P., S.G.R., S.A.G., P.J.L.), University of Washington, Seattle.ORCID 0000-0002-2541-4221
Ali ShojaieDepartment of Biostatistics (A.S.), University of Washington, Seattle.ORCID 0000-0001-8846-3533
Sina A GharibDepartment of Medicine (H.P., S.G.R., S.A.G., P.J.L.), University of Washington, Seattle.ORCID 0000-0002-2480-4367
Peter J LearyDepartment of Medicine (H.P., S.G.R., S.A.G., P.J.L.), University of Washington, Seattle.ORCID 0000-0001-5716-248X
Lu XiaDepartment of Statistics and Probability, Michigan State University, East Lansing (L.X.).ORCID 0000-0003-1561-6871

Funding

Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
Integrated Multi-omics of MelioidosisR01AI137111 · NIAID · UNIVERSITY OF WASHINGTON · PI GHARIB, SINA A, WEST, TIMOTHY EOIN · 2018 to 2021
$3.2M
REHAB-PH Trial: Repurposing a Histamine Antagonist to Benefit Patients with Pulmonary HypertensionR33HL142539 · NHLBI · UNIVERSITY OF WASHINGTON · PI LEARY, PETER J · 2019 to 2022
$2.7M
Machine Learning Tools for Discovery and Analysis of Active Metabolic PathwaysR01GM114029 · NIGMS · UNIVERSITY OF WASHINGTON · PI SHOJAIE, ALI · 2016 to 2020
$1.7M
Novel Statistical Inference for Biomedical Big DataR01GM133848 · NIGMS · UNIVERSITY OF WASHINGTON · PI SHOJAIE, ALI · 2020 to 2023
$1.7M
The Pulmonary Hypertension- Multi-Dimensional Omics to Characterize Right Heart Adaptation (PH-MOCHA) studyR01HL152724 · NHLBI · UNIVERSITY OF WASHINGTON · PI GHARIB, SINA A, LEARY, PETER J · 2020 to 2023
$1.6M
Proteomic Signatures Associated with Right Ventricular Failure and Mortality in Pulmonary Arterial HypertensionF32HL168780 · NHLBI · UNIVERSITY OF WASHINGTON · PI PI, HONGYANG · 2023 to 2024
$176k
NCATS NIH HHS KL2 TR000421NHLBI NIH HHS F32 HL168780NHLBI NIH HHS R01 HL152724NHLBI NIH HHS R33 HL142539NIAID NIH HHS R01 AI137111NIGMS NIH HHS R01 GM114029NIGMS NIH HHS R01 GM133848
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkershumansmetabolomicsmorbiditymortalityprognosisproteomics

Identifiers

PMID40899269
PMCPMC12577545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.